MCP -- Kislinger et al. 2 (2): 96 Table 2

TABLE II Summary of the cytochrome P450 isoforms detected in the microsomal membrane fractions of lung and liver

ID Liver Lung P450 isoform GO term Tissue specificity^a

C2F2 ${checkmark}$ ${checkmark}$ P450 2F2 Membrane Clara cells (lung and liver)

NCPR ${checkmark}$ ${checkmark}$ P450 reductase Membrane Liver microsomes

C39A ${checkmark}$ P450 39A1 Membrane Liver microsomes

CP4B ${checkmark}$ P450 4B1 Membrane Pulmonary microsomes (not found in liver)

CPBA ${checkmark}$ P450 2B10 Membrane Liver microsomes

CP12 ${checkmark}$ P450 1A2 Membrane Liver microsomes

CP3B ${checkmark}$ P450 3A11 Membrane Liver microsomes

CP3G ${checkmark}$ P450 3A16 Membrane Liver microsomes

CPAC ${checkmark}$ P450 2A12 Membrane Liver microsomes

CPB9 ${checkmark}$ P450 2B9 Membrane Liver microsomes

CPCT ${checkmark}$ P450 2C29 Membrane Liver microsomes

CPD9 ${checkmark}$ P450 2D9 Membrane Liver microsomes

CPDA ${checkmark}$ P450 2D10 Membrane Liver microsomes

CPE1 ${checkmark}$ P450 2E1 Membrane Highest level in liver

CPJ5 ${checkmark}$ P450 2J5 Membrane Wide tissue distribution

CPT7 ${checkmark}$ P450 17 Membrane No infomation

CPZ2 ${checkmark}$ P450 2C37 Membrane Liver microsomes

CPZ3 ${checkmark}$ P450 2C38 Membrane Liver, brain, kidney, and intestine (trace amounts in lung and heart)

CPZ4 ${checkmark}$ P450 2C39 Membrane Liver microsomes

CPZ5 ${checkmark}$ P450 2C40 Membrane Liver, brain, kidney, and intestine (trace amounts in lung and heart)

Q8VCX0 ${checkmark}$ P450 2d9 N/A^b Liver microsomes

Q99N18 ${checkmark}$ P450 CYP4F15 Monooxygenase High expression in liver and kidney, lower expression in brain

Q9DBW0 ${checkmark}$ RIKEN: 1200012E24 Monooxygenase No information

Q9JKY7 ${checkmark}$ P450 CYP2D22 Monooxygenase Most abundant in liver

Q9JMA7 ${checkmark}$ Cytochrome P450 Monooxygenase Liver microsomes

^{^a} Annotation obtained from Swiss-Prot.

^{^b} No GO term available.