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Originally published In Press as doi:10.1074/mcp.R400003-MCP200 on February 3, 2004.
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Molecular & Cellular Proteomics 3:302-310, 2004.
© 2004 by The American Society for Biochemistry and Molecular Biology, Inc.

Review

Clinical Infrastructures to Support Proteomic Studies of Tissue and Fluids in Breast Cancer*

Henning T. Mouridsen{ddagger} and Nils Brünner§,¶

From the {ddagger} Danish Breast Cancer Cooperative Group, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen, Denmark; and § Institute of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, Ridebanevej 3, 1870 Frederiksberg, Denmark

The Danish Breast Cancer Cooperative Group (DBCG) was established in 1977 with the aim to ensure optimal breast cancer diagnostics and therapeutic modalities on a nationwide basis. DBCG was organized in such a way so it represents a broad interdisciplinary collaboration with established clinical databases and biobanks. This review summarizes the infrastructures, such as those of the DBCG, that are required to facilitate translational research studies aiming at further diagnostic and therapeutic improvements through interactions directed at prevention, early diagnosis, and treatment of primary breast cancer.

To whom correspondence should be addressed: Institute of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, Ridebanevej 3, 1870 Frederiksberg, Denmark. Tel.: 45-35283130; Fax: 45-3535314; E-mail: nbr{at}kvl.dk


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