Originally published In Press as doi:10.1074/mcp.R800008-MCP200 on June 23, 2008.
Molecular & Cellular Proteomics 7:2038-2047, 2008.
© 2008 by The American Society for Biochemistry and Molecular Biology, Inc.
Review
Human Proteinpedia as a Resource for Clinical Proteomics*
Suresh Mathivanan , and
Akhilesh Pandey¶,||
From the Institute of Bioinformatics, International Tech Park, Bangalore 560 066, India, Department of Biotechnology, Kuvempu University, Shankaraghatta, Karnataka, India, and ¶ McKusick-Nathans Institute of Genetic Medicine and the Departments of Biological Chemistry, Pathology, and Oncology, Johns Hopkins University, Baltimore, Maryland 21205
Clinical proteomics is an emerging field that deals with the use of proteomic technologies for medical applications. With a major objective of identifying proteins involved in pathological processes and as potential biomarkers, this field is already gaining momentum. Consequently, clinical proteomics data are being generated at a rapid pace, although mechanisms of sharing such data with the biomedical community lag far behind. Most of these data are either provided as supplementary information through journal web sites or directly made available by the authors through their own web resources. Integration of these data within a single resource that displays information in the context of individual proteins is likely to enhance the use of proteomic data in biomedical research. Human Proteinpedia is one such portal that unifies human proteomic data under a single banner. The goal of this resource is to ultimately capture and integrate all proteomic data obtained from individual studies on normal and diseased tissues. We anticipate that harnessing of these data will help prioritize experiments related to protein targets and also permit meta-analysis to uncover molecular signatures of disease. Finally, we encourage all biomedical investigators to maximize dissemination of their valuable proteomic data to rest of the community by active participation in existing repositories such as Human Proteinpedia.
|| To whom correspondence should be addressed. E-mail: pandey{at}jhmi.edu

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Copyright © 2008 by the American Society for Biochemistry and Molecular Biology.
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