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Molecular & Cellular Proteomics 2:642-670, 2003.
© 2003 by The American Society for Biochemistry and Molecular Biology, Inc.

Program: Friday, October 10, 2003

89. CSBMCB-Roche Diagnostics Award Lecture
08:00–08:40, Room 710
89.1 The Role of Genomics in Cancer Research
Victor Ling, University of British Columbia, Vancouver, BC, Canada

90. Severo Ochoa Lecture
08:45–09:25, Room 710
90.1 TFIIH Enters the Clinic
Jean-Marc Egly, Institut de Génétique et de Biologie Moleculaire et Cellulaire, Strasbourg, France

09:25 Coffee Break

91. Concurrent Session 27
Splicing and Editing of RNA
Chair: Liam P. Keegan, Medical Research Council, Edinburgh, United Kingdom
Co-Chair: Benoit Chabot, Départment of Microbiology and Infectious Diseases, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada
09:35–12:45, Room 520CF
91.1 Proteins That Function at Early Stages of Spliceosome Assembly
Angela Krämer, University of Geneva, Geneva, Switzerland
91.2 Modulation of A-to-I Editing by Functional Nucleolar Sequestration
Ronald Emeson, Vanderbilt University, Nashville, TN, United States
91.3 Roles of the Proteins in the Trypanosome RNA Editing Complex
Barbara Sollner-Webb, The Johns Hopkins University School of Medicine, Baltimore, MD, United States
91.4 Editing Flies to Death
Liam P. Keegan, Medical Research Council, Edinburgh, United Kingdom

92. Concurrent Session 28
Education in the Molecular Life Sciences: The Central Role of Biochemistry and Biology
Chair: Cecilia Hidalgo, University of Chile, Santiago, Chile
Co-Chair: Ellis J. Bell, University of Richmond, Gottwald Science Center, Richmond, VA, United States
09:35–11:45, Room 514ABC
92.1 Bridging the Gap in Biochemistry Between Secondary School and University
Joan Guinovart, University of Barcelona, Barcelona, Spain
92.2 An "Inverted Pyramid" Approach to Upgrade Biology Teachers’ Skills That Starts with Newspaper Reports
Yedy Israel, Universidad de Chile, Santiago, Chile
92.3 More About Less: Defining the Essential Core
Robert Learmonth, University of Southern Queensland, Toowoomba, Australia
92.4 Education in the Molecular Life Sciences: The Central Role of Biochemistry and Molecular Biology
Ellis J. Bell, University of Richmond, Richmond, VA, United States

93. Concurrent Session 29
Mitochondrial Biogenesis and Evolution
Chair: Michael Gray, Dalhousie University, Halifax, NS, Canada
Co-Chair: Heidi McBride, University Of Ottawa Heart Institute, Ottawa, ON, Canada
09:35–11:05, Room 520BE
93.1 Diversity and Evolution of Mitochondrial Genome Architecture and Information Content
Gertraud Burger, Université de Montréal, Montréal, QC, Canada
93.2 Regulating Mitochondrial DNA Replication and Transcription
David Clayton, Howard Hughes Medical Institute, Chevy Chase, MD, United States
93.3 Diversity and Evolution of Mitochondrial RNA Editing Systems
Michael Gray, Dalhousie University, Halifax, NS, Canada

94. Concurrent Session 30
Cell Cycle Regulation
This session was made possible through an unrestricted educational grant by the Institute of Cancer Research/CIHR.
Chair: Elaine Elion, Harvard Medical School, Boston, MA, United States
Co-Chair: Dan Durocher, University of Toronto, Toronto, ON, Canada
09:35–11:05, Room 520AD
94.1 The Yeast Kinetochore Protein Complex and its Role in Genome Stability
Phil Hieter, University of British Columbia, Vancouver, BC, Canada
94.2 Regulatory Links Between Scaffold Proteins That Regulate MAPK Cascades and the Actin Cytoskeleton
Elaine Elion, Harvard Medical School, Boston, MA, United States
94.3 Regulation of the F-box Protein Skp2 by Growth Factors and Tumor Suppressors
Sylvain Meloche, Institut de Recherches Clinique de Montéal, QC, Canada

95. Concurrent Session 31
Apoptosis
This session was made possible through an unrestricted educational grant by the Institute of Cancer Research/CIHR.
Chair: Jerry Adams, Walter and Eliza Hall Institute, Melbourne, Australia
Co-Chair: Vincent Duronio, University of British Columbia, Vancouver, BC, Canada
09:35–11:05, Room 520CF Please note: This session has been rescheduled for 14:45–16:15
95.1 Life and Death Decisions at the Cellular Level
Jerry Adams, Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
95.2 Pathways to Granzyme-induced Death
Chris Bleackley, University of Alberta, Edmonton, AB, Canada
95.3 p53-dependent and -independent Apoptosis of Glioma Cells
Bozena Kaminska, Nencki Institute of Experimental Biology, Warsaw, Poland

96. Concurrent Session 32
Biochemistry and Molecular Biology of Severe Acute Respiratory Syndrome (SARS)
This session was made possible through unrestricted educational grants by the Institute of Infection and Immunity/CIHR and the Office of Vice-President Research University of British Columbia.
Chair: Bhagi Singh, University of Western Ontario, London, ON, Canada
Co-Chair: David Andrews, McMaster University, Hamilton, ON, Canada
09:35–11:05, Room 519AB
96.1 SARS Virus: A Bioinformatic Analysis
Chris Upton, University of Victoria, Victoria, BC, Canada
96.2 Structural Studies on Coronavirus Main Proteinases: Basis for the Design of Anti-SARS Drugs
Rolf Hilgenfeld, University of Luebeck, Luebeck, Germany
96.3 Science During Epidemic: Lessons from SARS
Frank Plummer, National Microbiology Laboratory, Winnipeg, MB, Canada

97. Concurrent Session 33
Mice, Protein, and Message
Chair: Alexander Archakov, Institute of Biomedical Chemistry of Rams, Moscow, Russia
09:35–11:05, Room 518ABC
97.1 Genetic Analysis of Apoptotic Pathways
Tak Mak, Princess Margaret Hospital, Toronto, ON, Canada
97.2 Protein-Protein Interactions as a Target for Drugs in Proteomics
Alexander Archakov, Institute of Biomedical Chemistry of Rams, Moscow, Russia
97.3 Integrating "Omic" Information: A Bridge Between Genomics and Systems Biology
Marc Vidal, Boston, MA, United States

11:05 Break

98. Concurrent Session 34
Transcription: RNA Polymerase and Transcription Factors
Chair: Mary Osborn, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany
Co-Chair: Gilles Lajoie, University of Western Ontario, London, ON, Canada
11:15–12:45, Room 520BE
98.1 DNA Damage Signaling to the TATA Box Binding Protein
Mike Schultz, University of Alberta, Edmonton, AB, Canada
98.2 Regulation of FCP1P, a Phosphatase that Acts Upon RNA Polymerase II in Saccharomyces cerevisiae
Caroline Kane, University of California, Berkeley, Berkeley, CA, United States
98.3 Regulation of Cell Fate by Combinational Interactions of Transcription Factors
Mona Nemer, Clinical Research Institute of Montreal, Montreal, QC, Canada

99. Concurrent Session 35
Mammalian and Fungal Prions
Chair: Roger Morris, King’s College London, London, United Kingdom
Co-Chair: Marica Bakovic, University of Guelph, Guelph, Ontario, Canada
11:15–12:45, Room 520AD
99.1 Mutational Control of Amyloid Conformations: Implications for the Generation of Prion Transmission Barriers
Jonathan Weissman, UCSF/HHMI, San Francisco, CA, United States
99.2 Structural Comparisons of the Recombinant and Natural Prion Protein
Simone Hornemann, Institute for Molecularbiology and Biophysics, Zürich, Switzerland
99.3 The Changing Membrane Environment of Mouse Prion Protein and Its Influence Upon Susceptibility to Pathogenic Conversion
Roger Morris, King’s College London, London, United Kingdom

100. Concurrent Session 36
In Vivo/Whole Body Metabolism by NMR and Spectroscopy
Chairs: Ian Smith, Institute for Biodiagnostics, Winnipeg, MB, Canada
Co-Chair: Carolyn Mountford, Institute for Magnetic Resonance Research, St. Leonards, Australia
11:15–12:45, Room 518ABC
100.1 A Spetroscopic Approach to the Early Diagnosis of Colon Cancer: NMR and IR
Ian Smith, Institute for Biodiagnostics, Winnipeg, MB, Canada
100.2 MRS Is in the Clinic and Improving Patient Management
Carolyn Mountford, Institute for Magnetic Resonace Research, Sydney, Australia
100.3 1H MR Spectroscopy and 23Na MR Imaging Correlates of Tissue Damage in Cerebral Ischemia
Robert Bartha, University of Western Ontario, London, ON, Canada

101. Concurrent Session 37
Integration of Signalling Pathways
Chair: Carlos Fernandez-Patron, University of Alberta, Edmonton, AB, Canada
Co-Chair: John Scott, Oregon Health Science University, Portland, OR, United States
11:15–12:45, Room 524ABC
101.1 Functional Responses to BCR-mediated Signaling Pathways Alter During B Cell Development
Margaret Harnett, University of Glasgow, Glasgow, United Kingdom
101.2 Signaling Through the Extracellular Signal-regulated Kinase (ERK) Cascade in Cardiac Myocytes
Angela Clerk, Imperial College London, London, United Kingdom
101.3 Molecular Organization of Cytoskeletal Transduction Complexes
John Scott, Howard Hughes Medical Institute, Portland, OR, United States

102. Concurrent Session 38
Proteomics: Past, Present, and the Future
Chair: Samir Hanash, Human Proteome Initiative Committee, University of Michigan, Ann Arbor, MI, United States
11:15–12:45, Room 519AB
102.1 Opportunities for Major Initiatives in Proteomics
Samir Hanash, Human Proteome Initiative Committee, University of Michigan, Ann Arbor, MI, United States
102A. Concurrent Session 38A
Clinical and Fundamental Advances in Proteomics
102A.1 The Oxidative Stress Response, as Viewed by Proteomics
Thierry Rabilloud, DRDC/BECP, CEA-Grenoble, France
102A.2 The Five Dimensions of Disease
Denis Hochstrasser, Geneva University Hospital, Geneva, Switzerland

103. Concurrent Session 39
Tissue to Discovery
This session was made possible through an unrestricted educational grant by the Ontario Genomics Institute.
Chair: Jim Woodgett, University of Toronto, Toronto, ON, Canada
14:45–16:15, Room 520BE
103.1 Next Generation in Microrrays
Jim Woodgett, University of Toronto, Toronto, ON, Canada
103.2 Metabolic Profiling and Functional Proteomics
David Wishart, University of Alberta, Edmonton, AB, Canada
103.3 Human Genome on a Chip for Stem Cell Research
Wilhelm Ansorge, EMBL, Heidelberg, Germany
Pharmaceutical Proteomics
Chair: Stanley Bellowski, United States
103.4 Integration of Proteomics with Pathology and Histology
Stanley Belkowski, United States
103.5 Proteomics in Drug Discovery and Development
Mark Molloy, Pfizer Global Research and Development, Ann Arbor Laboratories, MI, United States

104. Concurrent Session 40
Regulation of Myosin II in the Actin Cytoskeleton
Chair: Kristine Kamm, UT Southwestern Medical Center, Dallas, TX, United States
Co-Chair: Terry Hébert, Montreal Heart Institute, Montreal, QC, Canada
14:45–16:15, Room 524ABC
104.1 Regulation of Myosin Light Chain Kinase In Vitro and In Vivo
Kristine Kamm, UT Southwestern Medical Center, Dallas, TX, United States
104.2 Regulation of Myosin Phosphatase
David Hartshorne, University of Arizona, Tucson, AZ, United States
104.3 Regulation of Phosphorylation of Myosin Light Chain by Rho
Kozo Kaibuchi, Nagoya University Graduate School of Medicine, Nagoya, Japan

105. Concurrent Session 41
Educational Session: Nanotechnology
Chair: Stephan Dahms, San Diego State University College Sciences, San Diego, CA, United States
14:45–17:10, Room 514ABC
105.1 Microfluidics & Proteomics
Laurell Thomas, Lund Unversity, Lund, Sweden
105.2 Microfluidics and Proteomics
Fred Regnier, Purdue University, IN, United States
105.3 Protein Microarrays Main Session
Paul Predki, Yale University, New Haven, CT, United States
105.4 Genomics as an Alternative to Proteomics
Charles Cantor, Sequenom, Inc., United States

106. Oral Session 22
Proteomes of Human Tissues
Chair: Alexey Pshezhetsky, Montreal University-Service de Génétique Médicale, Hôpital Sainte-Justine, Montréal, QC,Canada
14:45–16:15, Room 518ABC
14:45 106.1 Systematic Analysis of Human Fetal Liver Proteome and Integration with Its Transcriptome
Fuchu He, Beijing Institute of Radiation Medicine, Beijing, P.R. China
14:57 106.2 Proteomic Analysis of Human Stem Cell Plasma Membranes by Mass Spectrometry
Patricia Anne-Marie Zeemann, University of Southern Denmark, Odense, Denmark
15:09 106.3 Multidimensional Proteome Profiling of Human Plasma
Michael Simonian, Beckman Coulter Inc., Fullerton, CA, United States
15:21 106.4 The Cerebrospinal Fluid Proteome: Quantification of the Differences Between the Ictal and Interictal States of Migraine
Roger Biringer, Thermo Electron, San Jose, CA, United States
15:33 106.5 Proteome Analysis of Cerebrospinal Fluids
Jerome Bailey, Proteomics Bioreagen, Agilent Technologies, Wilmington, United States
15:45 106.6 Removal of Albumin and IgG from Serum Facilitates Proteomic Analysis
David Colantonio, Queen’s University, Kingston, ON, Canada
15:57 106.7 Human Proteomes: New Advances and Challenges
Alexey Pshezhetsky, Associate Professor, Montreal University—Service de génétique médicale, Hôpital Sainte-Justine, Montreal, QC, Canada

107. Oral Session 23
Medical Proteomics—Other Diseases
Chair: Rafik Sekaly, University of Montreal, Montréal, QC, Canada
14:45–16:15, Room 520AD
14:45 107.1 Regulation of Matrix Metalloproteinases (MMPs), and Tissue Inhibitor of Metalloproteinases (TIMP) by Anti Transforming Growth Factor-B Antibodies, Lutein and Polipodium Leucotomos in Dermal Fibroblasts
Neena Philips, Georgian Court College, Lakewood, NJ, United States
15:03 107.2 Proteomic Analysis of Serum and Plasma by 2D DIGE and SELDI-MS: Application to Host-Pathogen Interactions
Brett Chromy, Proteomics Group Lea, Lawrence Livermore National Laboratory, Livermore, CA, United States
15:21 107.3 Proteomic Analysis of the Nucleocapsid Protein in SARS Coronavirus
Xu Ningzhi, Beijing Genomics Institute, Beijing, P.R. China
15:39 107.4 Characterization of the Molecular Machines Involved in Actin Remodelling Upon Ischemia and Reperfusion in Human Liver
Anouk Emadali, McGill University, Montréal, QC, Canada
15:57 107.5 The Entire Human Proteome and Its Relevance to the Establishment of "Self," "Non-self" and Autoimmunity
Ian Humphery-Smith, University of Utrecht, Utrecht, The Netherlands

108. Oral Session 24
Informatics—Bioinformatics Part I
Chair: Paul Kearney, Caprion Pharmaceuticals, Montréal, QC, Canada
14:45–16:15, Room 519AB
14:45 108.1 Proteomic Data Analysis—Integrating the Results from Complementary Workflows
David Fenyo, Amersham Biosciences AB, Uppsala, Sweden
15:00 108.2 Visualizing Proteomic Datasets
Donald Johann, National Institutes of Health, Bethesda, MD, United States
15:15 108.3 Engineering the Proteomics Analysis Pipeline for the Cellmap Project
Robert Kearney, McGill University, Montreal, QC, Canada
15:30 108.4 Impact of Replicate Analysis on Biomarker Discovery Using Mass Spectrometry
Nicole White, Johns Hopkins Medical Institutions, Baltimore, MD, United States
15:45 108.5 MALDI-TOF Data Analysis for Proteomic Biomarker Discovery
Yutaka Yasui, Fred Hutchinson Cancer Research Center, Seattle, WA, United States
16:00 108.6 Bioinformatics Tools for Biomarkers Discovery and Construction of Multivariate Predictive Models
Zhen Zhang, Johns Hopkins Medical Institutions, Baltimore, MD, United States

16:15 Coffee Break

109. Oral Session 25
Informatics—Bioinformatics Part II
Chair: Paul Kearney, Caprion Pharmaceuticals, Montreal, QC, Canada
16:30–18:00, Room 519AB
16:30 109.1 The Mouse Gene Expression Database (GXD)
Martin Ringwald, The Jackson Laboratory, Bar Harbor, ME, United States
16:52 109.2 Taggor-PepMap, a New Software Pipeline Using LC-MS/MS Data for Genome Annotation
Jérôme, Garin, CEA/Grenoble, Grenoble, France
17:14 109.3 Analysis of Proteomic Depth in Yeast Via Peptide-based Proteomics
Kenneth Parker, Applied Biosystems, Framingham, MA, United States
17:36 109.4 Indexing Schemes for Similarity Search of Short Protein Fragments
Aleksandar Stojmirovic, Victoria University of Wellington, Wellington, New Zealand

110. Concurrent Session 42
Local Calcium Signaling
Chair: Alexandra Zahradnikova, Slovak Academy of Sciences, Bratislava, Slovakia
Co-Chair: Ed Moore, Institute of Molecular Physiology and Genetics, Canada
16:30–18:00, Room 520BE
110.1 Structural Basis for Ca2+ Signalling
Mitsuhiko Ikura, Ontario Cancer Institute, Toronto, ON, Canada
110.2 Inositol Trisphosphate Receptors in the Heart: Trigger the Spark to Corrupt the Heart
Peter Lipp, University of the Saarland, Homburg/Saar, Germany
110.3 Calcium Signaling Events in the Cardiac Excitation-Contraction Coupling Unit
Alexandra Zahradnikova, Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Bratislava, Slovakia

111. Oral Session 26
HUPO Initiative—Plasma
Chair: Gilbert Omenn, University of Michigan, Ann Arbor, Michigan, United States
16:30–18:00, Room 524ABC
16:30 111.1 The HUPO Plasma Proteome Project Pilot Phase: Reference Specimens, Technology Platform Comparisons, and Standardized Data Submissions and Analyses
Gilbert Omenn, University of Michigan, Ann Arbor, Michigan, United States
16:45 111.2 Zooming in on Human Serum: Increasing Proteomic Coverage Using a 2-D Gel Approach
Emma McGregor, Proteome Sciences PLC, London, United Kingdom
17:00 111.3 Towards the Optimization of Conditions for SELDI-TOF Mass Spectrometric Analysis of a HUPO Reference Specimen
Alex Rai, The Johns Hopkins University School of Medicine, Baltimore, MD, United States
17:15 111.4 Highly Sensitive and Efficient, Multi-dimensional Analysis of Intact Proteins to Decipher the Human Serum Proteome in Graft-Versus-Host Disease
Hong Wang, University of Michigan, Ann Arbor, MI, United States
17:30 111.5 Identification of Plasma Proteins from Fractionated Sub-proteomes
Erik Forsberg, Amersham Biosciences AB, Uppsala, Sweden
17:45 111.6 2D-LC-MS/MS Analysis of Gradiflow Fractionated Native Human Plasma
Vicki Locke, Gradipore Inc., Hawthorne, NY, United States

112. Oral Session 27
Network Proteomics
Chair: David Thomas, McGill University, Montréal, QC, Canada
16:30–18:00, Room 520AD
16:30 112.1 Protein and Peptide Diagnostics by Immunoaffinity-Mass Spectrometry
Niels Heegaard, Statens Serum Institut, Copenhagen, Denmark
16:48 112.2 High Throughput Enabling Technologies to Study the Ras Superfamily of GTPases
Marie-Elaine Caruso, Royal Victoria Hospital, Montréal, QC, Canada
17:06 112.3 Application of Protein Array Technology to Study Protein-Protein Interactions and Protein-DNA Interactions
Harald Seitz, Max-Planck-Institute of Molecular Genetics, Berlin, Germany
17:24 112.4 Human Protein Reference Database—A Platform for Systems Biology
Akhilesh Pandey, Johns Hopkins University, Baltimore, MD, United States
17:42 112.5 Human Protein Interaction Map in the TGFbeta Signalling Pathway
Pierre Le Grain, CEA Saclay, Paris, France

113. Oral Session 28
HUPO Initiative—Liver
Chair: Fuchu He, Beijing Institute of Radiation Medicine, Beijing, P.R. China
Co-Chair: Christian Brechot, Inserm, France
16:30–18:00, Room 518ABC
16:30 113.1 Update Progress of Human Liver Proteome Project
Fuchu He, Beijing Institute of Radiation Medicine, Beijing, P.R. China
16:41 113.2 Proteomic Analysis of Interferon Signaling and Hepatitis C Virus—Host Protein Interaction Network in Human Liver Cells
Deborah Diamond, University of Washington, Seattle, WA, United States
16:52 113.3 Applications of Proteomics to ADME/Tox
Ola Ronn, Amersham Biosciences AB, Uppsala, Sweden
17:03 113.4 Copper Metalloproteomics: A Search for Proteins with Novel Copper Binding Ability
Scott D. Smith, University of Toronto, Toronto, ON, Canada
17:14 113.5 A Proteomic Approach to Identify Early Molecular Targets of Oxidative Stress in HEPG2 Liver Cells
Gianluca Tell, University of Trieste, Trieste, Italy
17:25 113.6 A Proteomic Approach to Identify a Sex-linked Potassium Channel in Rat Liver Plasma Membranes
Houria Abbas, Queen’s University, Kingston, ON, Canada
17:36 113.7 Human Liver Proteomics: Primary Intrahepatic Calculosis
Akira Tsugita, NEC Proteomics Center, Tsukuba, Japan
17:47 113.8 TBA
Christian Brechot, INSERM, France

113A. HUPO Plenary Lecture
This session was made possible through an unrestricted educational grant by McGill University
18:00–18:50, Room 710
113A.1 Structural Characterisation of Protein Post-translational Modifications Using a MALDI QIT TOF Mass Spectrometer
Koichi Tanaka, Shimadzu Corporation, Kyoto, Japan

114. Poster Session 37
HUPO Initiative—Plasma
114.1 Glycotyping of Serum Transferrin Isoforms by Capillary Zone Electrophoresis in Healthy Humans
Franz Jacques Legros, CHU André Vésale, Montigny-le-Tilleul, Belgium
114.2 Development of Human Serum Transferrin Isoforms from Newborns to Adults
Franz Jacques Legros, Chu André Vésale, Montigny-le-Tilleul, Belgium
114.3 Characterization of the Low Molecular Weight Serum Proteome
Timothy Veenstra, National Cancer Institute at Frederick, Frederick, MD, United States
114.4 High-throughput Identification of Plasma Proteins Using Multidimensional Liquid Chromatography Coupled with Ion Trap Mass Spectrometry
Leo Bonilla, Harvard Medical School-Partners Healthcare Center for Genetics and Genomics, Cambridge, MA, United States
114.5 Immunoaffinity Depletion of High-abundant Proteins from Human Serum for Proteomic Sample Preparation—Method Evaluation
Nina Zolotarjova, Agilent Technologies Inc., Wilmington, DE, United States
114.6 Proteomic Analysis of Human Plasma/Serum
Shu-Yu Lin, Insitute of Biological Chemistry, Taipei, Taiwan
114.7 Iron Chelators Prevent Inhibition of Tartrate-resistant Acid Phosphatase from Human Blood by Hydrogen Peroxide
Erika Anjos, State University of Campinas, Campinas, São Paulo, Brazil
114.8 Immunoaffnity Techniques for Human Plasma Proteomics
Kazuyuki Nakamura, Yamaguchi University School of Medicine, Ube, Japan
114.9 A Semi-automated Chromatographic Method for the Prefractionation of Plasma Proteins
Raf Lemmens, Amersham Biosciences, Uppsala, Sweden
114.10 Identification of Protein-Protein Interactions within Human Serum
Ming Zhou, SAIC-Frederick, Frederick, MD, United States
114.11 High-throughput Plasma Depletion with Chicken Antibodies for Proteomic Analysis
Sun Tam, Charles River Laboratories, Worcester, MA, United States
114.12 Depletion of High Abundant Proteins for Human Plasma Proteome Studies
Young Wang, Johns Hopkins Medical Institutions, Baltimore, MD, United States
114.13 Comprehensive Profiling of Human Plasma and Serum Proteomes Using Microsol-IEF Prefractionation and Major Protein Depletion
Lynn Echan, The Wistar Institute, Philadelphia, PA, United States
114.14 Proteome Analysis of Plasma and Serum Proteins Using a 3-D Strategy Combining Microsol-IEF, 1-D Gels, and LC-MS/MS
Nadeem Ali-Khan, The Wistar Institute, Philadelphia, PA, United States
114.15 Analysis of Peptides and Phospho Peptides from Protein and Phospho-Proteins Mixtures by Offline C18 LC-MALDI-Qq-TOF
John Marshall, Ryerson University, Toronto, Ontario, Canada
114.16 Apolipoproteins A: A Good Candidate Family of Cardiovascular Disease Biomarkers in Plasma
Cécile Cren-Olivé, Université des Sciences et Technologies, Villeneuve D’Ascq, France
114.17 Human Serum Proteins Pre-separated by Electrophoresis or Chromatography Followed by Tandem Mass Spectrometry
John Marshall, Ryerson University, Toronto, Ontario, Canada

115. Poster Session 38
Network Proteomics
115.1 Dutpase in the Drosophila Proteome
Angela Bekesi, Institute Enzymology, Budapest, Hungary
115.2 Isolation and Mass Spectrometry of Multi-Proteins Complex Regulating the Ras Signalling in Saccharomyces cerevisiae
Cécile Cren-Olivé, Université des Sciences et Technologies, Villeneuve D’Ascq, France

116. Poster Session 39
HUPO Initiative—Liver
116.1 Correlation Analyzes of Changes of Hepatocytes Chromatin Phospholipid Component After Vagotomy and Solarectomy
Ararat Minasyan, Yerevan State Medical University After Mkhitar Heratsi, Yerevan, Armenia
116.2 Serum Cysteine, Zinc and Copper in Cirrhosis
Suleyman Aydin, Firat University, Medical School, Elazig, Turkey
116.3 The Level of Homocysteine in the Cirrhotic Patients
Suleyman Aydin, Firat University, Medical Scool, Elazig, Turkey
116.4 Chronic Alcohol Consumption Inhibits Oxygenation Changes in the Livers of Live Rats—Noninvasive In Vivo Dynamic CT, Functional MRI and 31P MRS Studies
Manfred Brauer, University of Guelph, Guelph, ON, Canada
116.5 Glycotyping of Transferrin Isoforms and Ethanol
Franz LeGros, CHU André Vésale, Montigny-le-Tilleul, Belgium

117. Poster Session 40
Proteomes of Human Tissues
117.1 Phosphorylated Proteins Profiling of Human Fetal Liver
Yun Cai, Beijing Institute of Radiation Medicine, Beijing, P.R. China
117.2 Phosphorylated Proteins Profiling of Human Fetal Liver
Xiaohong Qian, Beijing Institute of Radiation Medicine, Beijing, P.R. China
117.3 Proteomic Analysis of Different Area of Different Aged Human Brains
Ji Jianguo, National Laboratory of Protein Engineering and Plant Genetic Engineering, Beijing, P.R. China
117.4 Profiling of the Proteomes in Human Tissues by In-gel Isoelectric Focusing and Mass Spectrometry
Sarka Beranova-Giorgianni, University of Tennessee Health Science Center, Memphis, TN, United States

118. Poster Session 41
Lipid Rafts and Caveolae
118.1 Alkyl-lysophospholipid Induces Apoptosis After Lipid Raft-mediated Endocytosis, Whereas Lysophosphatidylcholine, Preventing This Apoptosis, Internalizes by Trans-Membrane Flipping
Wim. J. van Blitterswijk, The Netherlands Cancer Institute, Amsterdam, The Netherlands
118.2 Isolation and Characterization of Different Subsets of Lipid Rafts from the RBL-2H3 (Rat Basophilic Leukemia) Cell Line
Galina Radeva, University of Guelph, Guelph, ON, Canada
118.3 Cathepsin B Localizes to Plasma Membrane Caveolae in Differentiating Myoblasts: A Role for Cathepsin B
Derek Jane, University of Windsor, Windsor, ON, Canada
118.4 Association of LDL Receptor Related Protein (LRP1) with the Detergent Insoluble Membranes in 3T3-L1 Fibroblasts and Adipocytes Treated with Insulin
Hongyu Zhang, University of Ottawa Heart Institute, Ottawa, ON, Canada
118.6 The Proteome of Phagosome Lipid Microdomains: Further Insights into Phagosome Functions
Guillaume Goyette, Université de Montréal, Montréal, QC, Canada
118.7 Assembly of CXCR1 During Chemotaxis in Response to CXCl8
Ravi Ramjeesingh, University of Toronto, Toronto, ON, Canada
118.8 Pin-B, a Plant Seed Lipid-Binding Protein Can Reduce Secreted Apolipoprotein B Levels in McArlde Cells
Kechun Wu, University of Ottawa, Ottawa, ON, Canada

119. Poster Session 42
Regulation of Signal Transduction by Lipid Mediators
119.1 Effect of UV-C Irradiation on the Activity Modulation of Phospholipase D in Vero76 Cells
Sungyeul Kim, Seoul National University, Seoul, South Korea
119.2 Haploinsufficiency of the Pten Lipid Phosphatase Induces Insulin Hypersensitivity
Jason Wong, University of British Columbia, Vancouver, BC, Canada
119.3 TLC Evidence on the In Vitro Formation of N-acyl Phosphatidyl Ethanolamine by Endogenous Components of Rabbit Kidney
Fatma Helmy, Delaware State University, Dover, DE, United States
119.4 Studies on the Endogenous Phospholipids of Mammalian Kidney and their In Vitro Hydrolysis by Endogenous Phospholipases
Mohamed Hassanein, University of Delaware, Dover, DE, United States
119.5 PLC Delta1 Is Required for Hair Follicle Formation
Yoshikazu Nakamura, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
119.6 SKIP, a PIP3 Phosphatase, Negatively Regulates Insulin-induced GLUT4 Translocation and Membrane Ruffling Formation
Takeshi Ijuin, Institute of Medical Science, University of Tokyo, Tokyo, Japan
119.7 Phospholipase C Delta1 Is Required for Hair Follicle Formation
Yoshikazu Nakamura, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
119.8 HIF-1alpha Protein Is a Potential Target for S-Nitrosation
Vadim Sumbayev, University of Kaiserslautern, Kaiserslautern, Germany
119.9 Activation of p21-activated Kinase 1 Is Necessary for Lysophosphatidic Acid-induced NIH3T3 Cell Motility
Hoi Lee, College of Medicine, Konyang University, Nonsan, South Korea
119.10 Signaling Pathways Controlling Low Density Lipoprotein Expression by Intracellular Calcium in Hepatic Cells
Kamal Mehta, Ohio State University College of Medicine, Columbus, OH, United States
119.11 Lipase Super-induction from Several Pseudomonas Strains by Fatty Alcohols
Morio Ishizuka, Chuo University, Tokyo, Japan
119.12 Evidence for Fatty Acid-induced Insulin Resistance in a Cultured Muscle Cell Line, C2C12: Differential Effects of Fatty Acid Species on Insulin Signaling Pathway
Rafik Ragheb, University Health Network, Toronto, ON, Canada
119.13 Lipid Phosphate Phosphatase-2 Regulates Proliferation and Cell Cycle Progression in Rat 2 Fibroblasts
Katherine Morris, University of Alberta, Edmonton, AB, Canada
119.14 Cdk5 Is Involved in Neuregulin-dependent Activation of PI-3 Kinase and Akt Activity Mediating Neuronal Survival
Bing-Sheng Li, NINDS, NIH, Bethesda, MD, United States
119.15 PC-1 Phosphodiesterase Activity in a Type II Diabetic Animal Model
Donovan McGrowder, The University of the West Indies, Kingston, Jamaica

120. Poster Session 43
Membrane Protein Structure and Dynamics
120.1 Contribution of Negatively and Positively Charged Residues in S2, S3 and S4 to the Final Membrane Topology of the Voltage Sensor in the Potassium Channel, KAT1
Yoko Sato, Kyushu University, Fukuoka, Japan
120.2 NMR Investigations of the Structure of Myelin Basic Protein
David Libich, University of Guelph, Guelph, ON, Canada
120.3 Structural and Functional Characterization of P-Glycoprotein Catalytic Transition State Complexes
Paula Russell, University of Guelph, Guelph, ON, Canada
120.4 Heteronuclear NMR Spectroscopy of the Integral Membrane Protein Glycerol Facilitator
Jamie Galka, University of Manitoba, Winnipeg, MB, Canada
120.5 Spin Label Study of the Interaction Between Triton X-100 and Red Blood Cells
Paulo Preté, State University of Campinas-UNICAMP, Campinas, Brazil
120.6 Molecular Cloning of a Novel K+-dependent Na+/Ca2+ Exchanger
Xinjiang Cai, University of Calgary, Calgary, AB, Canada
120.7 Structure of the Yeast Saccharomyces cerevisiae Protoporphyrinogen Oxidase: Homology Modeling and Biochemical Studies of the Active Site Topology
Alexandra Benevant, Institut Jacques Monod, Paris, France
120.8 The Molecular Environment Surrounding Yeast Mitochondrial F1F0-ATP Synthase Subunit 8
Phillip Nagley, Monash University, Victoria, Australia
120.9 Solution Behaviour of TonB from Escherichia coli: Self Association and Interactions with an Outer Membrane Receptor
Peter Pawelek, McGill University, Montréal, QC, Canada
120.10 Interaction Analysis of the Bacterial Outer Membrane Protein FhuA and its Energy Transducing Partner TonB
Cezar Khursigara, McGill University, Montréal, QC, Canada
120.11 Molecular Interactions of Bacterial Outer Membrane Transporters and the Energy-transducer TonB
Jean-Nicolas Gagnon, McGill University, Montréal, QC, Canada
120.12 The Na+/H+ Exchanger Cytoplasmic Tail: Structure, Function and Interactions with Tescalcin
Xiuju Li, University of Alberta, Edmonton, AB, Canada
120.13 Mutation of Structurally Important Residues Abolishes the Activity of Na+/H+ Exchanger Isoform
Emily Slepkov, University of Alberta, Edmonton, AB, Canada
120.14 Kinetic Analysis of Protein Palmitoylation: Is Exponential Decay an Appropriate Description?
Riad Qanbar, Université de Montréal, Montréal, QC, Canada
120.15 Structural Characterization of Equilibrative Nucleoside Transporters
Imogen Coe, York University, Toronto, ON, Canada
120.16 Expression Purification and Characterization of Bacillus subtilis BsSCO, a Membrane Protein Involved in a Cytochrome C Oxidase Assembly
Iveta Imriskova-Sosova, Queen’s University, Kingston, ON, Canada
120.17 Insights into the Model of the Integral Membrane Protein EmpE Through Lipid Face Prediction and Disulfide Crosslinking
Tara L. Winstone, Research Assistant, University of Calgary, Calgary, AB, Canada
120.18 Structural Analysis of Neurospora crassa Mitochondrial Porin in Detergent Systems
Denice Bay, University of Manitoba, Winnipeg, MB, Canada
120.19 Elucidating the Functional Mechanics of ABC Transporters
Eliud Oloo, University of Calgary, Calgary, AB, Canada
120.20 Fluorescence Characterization of the Interaction of LDS-751 and Rhodamine 123 With P-Glycoprotein: Evidence for Simultaneous Binding of Both Drugs
Frances Sharom, University of Guelph, Guelph, ON, Canada
120.21 Structural Analysis of the HflKC Complex of Escherichia coli
Lee-Ann Briere, The University of Western Ontario, London, ON, Canada
120.22 Functional Expression and Cellular Localization of the Na+/H+ Exchanger, Sod2, of the Fission Yeast Schizosaccharomyces pombe
Christine Wiebe, University of Alberta, Edmonton, AB, Canada
120.23 Structural Studies of the Neuropeptide Methionine-Enkephalin in Monoolein Cubic Phases Using Nuclear Magnetic Resonance Spectroscopy
Laila M. R. Singh, Simon Fraser University, Burnaby, BC, Canada
120.24 Heteromeric Versus Homomeric Expression of Inwardly Rectifying K+ Channels Suggests Different Microenvironments Near the Pore
Hung Lam, Queen’s University, Kingston, ON, Canada
120.25 Lipid-Protein Interactions of a Mechanosensitive Ion Channel (MscL)
Andrew Powl, University of Southampton, Southampton, United Kingdom

121. Poster Session 44
Proteins in Pathology and Therapy
121.1 Modification of Cryptic Splice Site in Beta-glucosidase cDNA Increases Expression Yield: Implication for Treatment of Gaucher Disease
Scott Bukovac, Hospital for Sick Children/University of Toronto, Toronto, ON, Canada
121.2 Evaluation of Human Serum Albumins Produced in Iran Based on Total Protein
Monirossadat Haerian, Food & Drug Control Laboratories, Tehran, Iran
121.3 Catalytic Activities of Platelet Enzymes (Glutamate Dehydrogenase, Rotenone-Insensitive Cytochrome C Reductase and Isocitrate Dehydrogenase) in Relation to Alzheimer Disease
Frouzandeh Jalilvand, Institute of Biochemistry & Biophysics, Tehran, Iran
121.4 Liposomes Containing Epidermal Growth Factor (EGF): Encapsulation Characteristics and the Immune Response in Mice
María Del Carmen Luzardo Lorenzo, University of Havana, Faculty of Biology, Habana, Cuba
121.5 DNA-based Vaccination Using Multiple Schistosoma mansoni Genes
Mohamed Saber, Theodore Bilharz Research Institute, Giza, Egypt
121.6 Effect of Alcohols and Organic Solvent on Neocarzinostatin—A Molecular View of the Drug Delivery System
Christopher G. Sudhahar, Natioanl Chung Hsing University, Taichung, Taiwan
121.7 Shigella Enterotoxin Alters Enterocyte Differentiation and Is Associated with Declined Intestinal Antioxidant Status in Mice
Bamidele Iwalokun, University of Lagos, Lagos, Nigeria
121.8 Analysis of Tumour Suppressor p53 Protein Binding Properties by New ELISA Technique
Vaclav Brazda, Institute of Biophysics Academy of Sciences, Brno, Czech Republic
121.9 Comparative Analysis Between Two Tests for Determining Fetal Lung Maturity
Aleksandra Atanasova, University St Cyril & Methody, Skopje, Macedonia
121.10 Induction of Neutralizing Antibodies Against Herpes Simplex Virus Type 1 in BALB/c Mice Inoculated with Recombinant pCDNA3-gD or pCDNA3-gB or Both of Them
Mohammad Aghaebrahimian, Tarbiat Modarres University, Tehran, Iran
121.11 Autoantibodies Against DNA Topoisomerase I from Human Systemic Sclerosis Patients Cross-React with a Fibroblast Surface Antigen
Mélanie Tremblay, Hopital Notre-Dame, CHUM, Montréal, QC, Canada
121.12 Protection Against Hypoxic Insult in Cardiac Cell by HSP70 Protein Transduction
Jun Hye Kwon, Yonsei University College of Medicine, Seoul, South Korea
121.13 Haploinsufficiency of ATP2A2, Encoding the Sarco(endo)plasmic Reticulum Ca²⁺-ATPase Isoform 2, Predisposes Mice to Squamous Cell Carcinomas
Vikram Prasad, University of Cincinnati, Cincinnati, OH, United States
121.14 Isolation and Characterization of Mycobacterium bovis 19 kDa Native Protein Distinct from MPB 70/80
Elvira Varela, Instituto Nacional de Cardiologia, México, México
121.15 Peptide Decoys as a Potential Solution to Block Anti-FvIII Antibodies in Hemophilia a Patients?
Sylvie Villard, Institut de Biotechnologie et Pharmacologie, Montpellier, France
121.16 Tissue Inhibitor of Metalloproteinases 4 (TIMP-4) Expression and Function in Cervical Carcinoma
Floria Lizárraga, Instituto Nacional de Cancerologia, México, Mexico
121.17 Free and IgG-bounded Fibronectin in Sclerodermia Systematica
Anna Peleshenko, Dniepropetrovsk State Medical Academy, Dniepropetrovsk, Ukraine
121.18 Liposomes as an Attractive Adjuvant to Modulate the Immune Response Against Human Recombinant EGF (hrEGF)
Maria del Carmen Luzardo, University of Havana, Faculty of Biology, Ciudad Habana, Cuba
121.19 The TGF-beta1 Promoter Is Induced by HPV-16 E6 and E7 Oncoproteins in Cervical Cancer
Oscar Peralta Zaragoza, National Institute of Public Health, Cuernavaca, Morelas, Mexico
121.20 IgG Glycosylation in Composition of IgG-Fibronectin Complexes in Normal Pregnancy and Pre-eclampsia
Anna Maslak, Dnepropetrovsk State Medical Academy, Dnepropetrovsk, Ukraine
121.21 Interactions of Connective Tissue Growth Factor and Vascular Endothelial Growth Factor in Human Airway Smooth Muscle
Janette Kay Burgess, University of Sydney, Sydney, Australia
121.22 Surface Immobilized BMP-2 on Implants—A Novel Application
Maria Chatzinikolaidou, University of Essen, Essen, Germany

122. Poster Session 45
Molecular Structure, Simulation, and Evolution
122.1 Survey of Chitinase Genes Polymorphism in Iranian Rice Varieties
Nastaran Heidari, Tehran University, Tehran, Iran
122.2 The Related Species Revert Us to the Problem of Abundant Eukaryotic Genomes
Nadir Mamilov, Kazakh National University, Almaty, Kazakhstan
122.3 A Novel Carboxypeptidase-like Enzyme and Its Inhibitor from the Annelid Marine Sabellastarte magnifica
Maday Alonso Del Rivero Antigua, Universidad de La Habana, La Habana, Cuba
122.4 Isolation, Sequencing and Cloning of a Newfound Hyperthermostable Alpha-Amylase Gene from a Native Strain of Bacillus licheniformis and its Expression in Escherichia coli
Maryam Shahhoseini, Tehran University, Tehran, Iran
122.5 Molecular Evolution of Bioelectron Transfer: Hydrophobicity Conservation in the Docking Surfaces of Redox Protein Partners
Mario Fragata, Université du Québec a Trois-rivieres, Trois-Rivieres, QC, Canada
122.6 Myrosinase and Alliinase, Enzymes with Functional and Structural Similarities
Ghader Bashiri, Ramin Agricultural Research Centre, Ahwaz, Iran
122.7 Different Methylation Status of Human-specific LTRs That Integrated in Regulatory Gene Regions
Konstantin Khodosevich, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia
122.8 DTT-induced In Vitro Autocleavage of Human Hedgehog Protein’s Hint Domain
Pei-Lin Chen, Dalhousie University, Halifax, NS, Canada
122.9 Structural Analysis of Monomeric Isocitrate Dehydrogenase from Corynebacterium glutamicum
Fumie Imabayashi, University of Saskatchewan, Saskatoon, SK, Canada
122.10 Melting of DNA Complexes with Cis-Diaminedichlorplatinum (II) at Acidic pH
Samvel Haroutiunian, Yerevan State University, Yerevan, Armenia
122.11 Binding of New Meso-Tetra-(3N-Pyridil) Porphyrins to DNA
Yeva Dalyan, Yerevan State University, Yerevan, Armenia
122.12 Protein Evolution In Vitro: Design, Cloning and Expression of Modular B-Propeller Domains Using an Idealized WD Repeat
Maryam Nikkhah, University of Tehran, Tehran, Iran
122.13 Split Inteins with Protein Trans-Splicing Activities
Wenchang Sun, Dalhousie University, Halifax, NS, Canada
121.14 NMR Studies of TcUBP-1, a mRNA Destabilizing Factor from Trypanosoma cruzi
Laurent Volpon, McGill University, Montréal, QC, Canada
122.15 Structural and Functional Studies of Nitrite Reductase Type I Copper Site Mutants Bound with Exogenous Ligands
Sylvie Villard, University of British Columbia, Vancouver, BC, Canada
122.16 Conformational Changes of a Peptide from HIV-1 p24 Protein Induced by Ionic Micelles
Patricia Targon Campana, Universidade de São Paulo, São Carlos, Brazil
122.17 Use of Phage P2 a Protein for the Display of Random Peptide Libraries
Wenhua Cao, Jilin University, Changchun, China
122.18 Purification and Characterization of a Novel NADP+-linked Alcohol Dehydrogenase from Euglena gracilisZ
Iqbal Munir, Osaka Prefecture University, Osaka, Japan
122.19 Codon Usage in Cyprinidae Fishes, Evidence of Translational Selection
Alejandro Zavala, Universidad de la República, Montevideo, Uruguay

123. Poster Session 46
Molecular Basis of Developmental Biology
123.1 Production of Herpes Simplex Type-I Thymidine Kinase Recombinant Protein in E. coli
Shahrzad Rahimi Zadeh, Tarbiat Modarres University, Tehran, Iran
123.2 Application of Baculovirus Expression System to Produce Recombinant Glycoprotein G of Herpes Simplex Virus Type—In Order to Develop an ELISA Test
Keivan Zandi, Tarbiat Modarres University, Tehran, Iran
123.3 Functional Interaction Between the Nuclear Receptor RXRgamma and ZNF74, a Zinc Multifinger Protein Potentially Implicated in the DiGeorge Syndrome
Karl-Frédérik Bergeron, Simon Fraser University, Burnaby, BC, Canada
123.4 From Stem Cells to the Skeleton—Differentiation of ES Cells into Osteoblasts and Chondrocytes
Nicole Zur Nieden, University of Calgary, Calgary, AB, Canada
123.5 Withdrawn
123.6 Characterization of Transgenic Drosophila Synthesizing a Small Heat Shock/Alpha-Crystallin Protein from Artemia franciscana
Yu Sun, Dalhousie University, Halifax, NS, Canada
123.7 Regulation of FOXC1 Expression by PAX3, GLI2 and ß-Catenin During Myogenesis
Josee Savage, The University of Western Ontario, London, ON, Canada
123.8 BMP Regulates Skeletal Myogenesis at Two Steps
Karen Kerr, University of Western Ontario, London, ON, Canada
123.9 Characterization of a Novel Function of Bone Morphogenetic Proteins Type II Receptor (BMPRII) in Neuronal Development
Si Tuen Lee-Hoeflich, University of Toronto, Toronto, ON, Canada
123.10 Essential Role of C. elegans ARP2/3 Complex for Cell Migration During Ventral Enclosure
Mariko Sawa, Institute of Medical Science, University of Tokyo, Tokyo, Japan
123.11 Injection of DNA into Both Pronuclei Decreases Mosaicism in Early Mouse Embryos
Reza Kheirkhahi Oqani, Azad University, Science & Research Branch, Tehran, Iran
123.12 Development of a Clone of BK Cells and its Usage for Propagation of Parainfluenza 3 Virus and Herpes Simplex Virus Type 1
Mohammad Hassan Roostaee, Tarbiat Modarres University, Tehran, Iran
123.13 Proteomic Analysis of Early Craniofacial Development in Chicken Embryos
Choong Won Kim, Gyeongsang National University, College of Medicine, Jinju, South Korea
123.14 The Metabolism of Fluorescent End Products of Lipid Peroxidation
Jiri Wilhelm, Charles University, Prague, Czech Republic
123.15 Oxidative Damage to Lipids and Proteins in Tobacco Leaves of Different Age with High or Low Cytokinin Levels
Nada Wilhelmova, Institute of Experimental Botany and Academy of Science, Czech Republic, Prague, Czech Republic
123.16 BMP-2-induced Differentiation of Pluripotent NT2/D1 Human Embryonal Carcinoma Cells Involves Parallel Suppression of Neurogenesis Pathways and Induction of Epidermal Pathways
Rajendrakumar Chadalavada, Memorial Sloan-Kettering Cancer Center, New York, NY, United States
123.17 A 435 bp Upstream Region of the Liver-type Fatty Acid Binding Protein (L-FABP) Gene Is Sufficient to Modulate its Liver Regional Expression in Transgenic Zebrafish
Jen-Leih Wu, Academia Sinica, Taipei, Taiwan
123.18 Nucleotide Sequence of Creatine Kinase from the Cephalochordate Branchiostoma belcheri and the Properties of the Gene Product by Escherichia coli
Yoshida Mitsutaka, Fukui University of Technology, Fukui, Japan
123.19 Withdrawn
123.20 Purification and Characterization of Major Gelatin-Cleavage Activities in the Apically Located Extracellular Matrix of the Sea Urchin Embryo
Lavanya Ranganathan, Memorial University of Newfoundland, St. John’s, NF, Canada
123.21 Kinetics of Hoxd1 Protein Binding to the Promoter Region of Myelin Oligodendrocyte Glycoprotein
Jayaum Booth, University of Saskatchewan, Saskatoon, SK, Canada
123.22 Neurospora crassa Catalase-Peroxidase in Fungal Differentiation and Stress Tolerance
Leonardo Peraza, Institute of Cellular Physiology, National University of Mexico, Mexico, D.F., Mexico
123.23 Tid-1, a Human DnaJ Protein, Associates with the Trk Family of Receptor Tyrosine Kinases
Hui-yu Liu, Robarts Research Institute, London, ON, Canada
123.24 Proteomic Analysis of Human Embryonic Stem Cells
Je Kyung Seong, Seoul National University, Seoul, South Korea
123.25 Identification of KOX 1 Specific Target Genes by Microarray-analysis
Hans-juergen Thiesen, University of Rostock, Rostock, Germany
123.26 Molecular Biology and Gene Transformation in Brassica napus by Agrobacterium
Masoomeh Peyman, Islamic Azad Takestan University, Young Research Club, Iran, Qazvin, Iran
123.27 X-ray Crystallographic and Scanning Electron Microscopic Analysis of Starches from Five Yam (Dioscorea spp.) Varieties Grown in Jamaica
Cliff Riley, University of the West Indies, Mona, Kingston, Jamaica
123.28 Myostatin Signals Through a TGFB-like Signalling Pathway to Block Adipogenesis and Osteogenesis
Anuradha Rebbapragada, University of Toronto, Toronto, ON, Canada
123.29 Withdrawn

124. Poster Session 47
Molecular Medicine
124.1 The Effect of Continued Diabetes on the Formalin Induced Pain and Baclofen Analgesia in Rat
Elaheh Nooshinfar, Shaheed Beheshti University, Tehran, Iran
124.2 Ethanol and Transferrin Glycosylation
Franz Jacques Legros, CHU André Vésale, Montigny-le-Tilleul, Belgium
124.3 The Influence of Sarcolizin on Electrical Resistance of Bilayer Membranes and Free Radical Oxidation
Naira Sargsyan, Yerevan State University, Yerevan, Armenia
124.4 The Alteration of Electrical Conduction of Bilayer Membranes by Action of Some Anti-inflammatory Drug Plants
Astghik Sukiasyan, Yerevan State Univeristy, Yerevan, Armenia
124.5 Blindness: The Special Schools Serious Need for Genetic Counseling in Iran
Batoul Sadat Haerian, Tehran Regional Education Organization (TREO), Ministry of Education, Tehran, Iran
124.6 Mapping Genes for Resistance to Gastrointestinal Nematode Infection in Mice
David Menge, International Livestock Research Institute, Nairobi, Kenya
124.7 Cytotoxic and Genotoxic Effects of Action of Porphyrins and Their Metal Complexes on Human Blood Lymphocytes
Grigor Gyulkhandanyan, Institute of Biotechnology, Yerevan, Armenia
124.8 CPG Methylations in the Promoters of ER a and ER b Frequently Occur at or in Proximity to the Binding Sites of Transcriptional Factors in the Breast Cancer
Sun Jung Kim, Dongguk University, Seoul, South Korea
124.9 Anti Sense GM-CSF Construct Using Shuttle Vector
Naimeh Rafatian, Institute of Biochemistry and Biophysics, Tehran, Iran
124.10 Suppression of Metastatic Cancer Cell Invasion by Myosin Light Chain Kinase Inhibitor
Rutaiwan Tohtong, Mahidol University, Bangkok, Thailand
124.11 Effect of Acute Hypoxia on Lipid Alterations of Rats’ Brain, Liver and Myocardium During Autolysis In Vitro
Gennady Gribanov, Effect of Acute Hypo, Tver State University, Tver, Russia
124.12 Survival and Natural Killer Cell Activity in Tumor-bearing Mice Treated with Dehydrocrotonin, a Diterpene Lactone Isolated from Croton cajucara
Patricia Melo, Unicamp, Campinas, Brazil
124.13 Central Role of the Proteaosme in Senescence and Survival of Human Fibroblasts: Induction of a Senescence-like Phenotype Upon its Inhibition and Resistance to Stress Upon its Activation
Niki Chondrogianni, National Hellenic Research Foundation, Athens, Greece
124.14 Inhibiting Virus Replication at the DNA Level Using Group II Introns for Anti-HIV Gene Therapy
Reza Nazari, University of Toronto, Toronto, ON, Canada
124.15 Age-dependent Changes of Glucose Metabolism in Rat Liver During Immobilization Stress
Vadim Davydov, Institute of Children and Adolescent Health Protection, Kharkov, Ukraine
124.16 Preparation of Human Preproinsulin cDNA from Human WBC Genome
Farzaneh Pourasgary, University of Tehran and Biophysics, Tehran, Iran
124.17 Comparison of Western Blotting Method with Virus Neutralization Test for Measuring Herpes Simplex Virus Type 1 (HSV-1) Antibodies
Zahra Meshkat, Tarbiat Modarres University, Tehran, Iran
124.18 Alpha-1-Antitrypsin Phenotypes Presenting as Chronic Liver Disease in Children in Northern India
Anjali Ahuja, All India Institute of Medical Sciences, New Dehli, India
124.19 Oxidative Stress-induced Alterations of Gene Expression in Human Skin Fibroblasts Harboring A8344G Mitochondrial DNA Mutation
Yi-Shing Ma, National Yang-Ming University, Taipei, Taiwan
124.20 Inhibition of Androgen Action in Prostate Cancer Cell Lines by the Dual 5-Reductase Inhibitor, Dutasteride
Matthew Robichaud, Dalhousie University, Halifax, NS, Canada
124.21 Molecular Characterization of Hemagglutinin Gene of Influenza A/H1N1 Virus in the 2001–2002 Season
Mann-Jy Chen, Wyeth Vaccine Research, Pearl River, NY, United States
124.22 p53 Polymorphisms and Haplotypes in Jordanian Ethnic Groups, Breast Cancer and Lung Adenocarcinoma Patients
Amjad Mahasneh, Jordan University of Science and Technology, Irbid, Jordan
124.23 Development of a High-throughput Molecular Assay for Assessing Cell-mediated Immunity
Mann-Jy Chen, Wyeth Vaccine Research, Pearl River, NY, United States
124.24 Construction of a HFAB Phage Display Library from Patients with Osteosarcoma
Carmela Dantas-Barbosa, Sarah Network of Hospitals for the Locomotor System, Brasilia, Brazil
124.25 The Apolipoprotein E e4 Allele Is No Risk Factor for Turkish Breast Cancer Patients
Nilufer Bozkurt, Institute for Experimental Medical Research, Istanbul, Turkey
124.26 Ras and p53 Gene Mutations in Iranian Bladder Cancer Patients
Navaz Karimian Pour, Tehran University, Tehran, Iran
124.27 Mutant UvrB Recognition and Incision Characteristic of Polypeptide-DNA Cross-link
Zhengguan Yang, East Tennessee State University, Johonson City, TN, United States
124.28 Proteome Analysis of Regulatory T Cells—Promising Targets for Innovative Immunotherapeutical Approaches
Petra Weingarten, Protagen AG, Dortmund, Germany
124.29 Detection of bcr/abl Fusion in CML Patients by Interphase Fluorescence In Situ Hybridization
Seyed Mahmoud Tabatabaei, Islamic Azad University of Tabriz, Tabriz, Iran
124.30 Cytokine Responses of Bone and Cartilage Cells
Joyce Wai Sze Yip, Queen’s University, Kingston, ON, Canada
124.31 Biochemical Characterisation of Pseudomonas Species from Semi Arid Region Uzbekistan
Dilfuza Egamberdiyeva, Uzbek Academy of Sciences, Tashkent, Uzbekistan
124.32 Phosphorylation of the Potyvirus Capsid Protein by Protein Kinase CK2 Is Essential for Viral Infection
Konstantin Ivanov, University of Helsinki, Helsinki, Finland
124.33 Anoxia Causes Accumulation, Transcriptional Activation and Cross-talk Between p53 and HIF-1
Tobias Schmid, University of Kaiserlautern, Kaiserlautern, Germany

125. Poster Session 48
Tissue to Discovery Posters
125.1 Scoring and Docking Studies of the SARS-CoV Mpro Binding with a Few Inhibitors
Dongqing Wei, Tianjin Institute of Bioinformatics and Drug Discovery, Tianjin, P.R. China
125.2 Proteomic Analysis of Proteins Specifically Binding to Potential LTR HERV-K Regulatory Element
Dmitrii Trubetskoy, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia
125.3 QSAR Models of the 3-Aminoflavonoid Group: Linear Regression vs. Neurofuzzy Logic
Pham Van Tat, University of Dalat, Dalat, Vietnam
125.4 Fab End of a Fascinating Story of the Development of Novel Anti-malarials
Avadhesha Surolia, Indian Institute of Science, Bangalore, India
125.5 Histone H1 as a Target for Anthracycline Antibiotics
Azra Rabbani, University of Tehran, Tehran, Iran
125.6 Gene Expression Profile of SOCS2 Knockout: Defining the Set of Genes Involved in Somatic Growth Using Microarray Assay
Elizabeth Rico-Bautista, Karolinska Institute, Stockholm, Sweden
125.7 Trace Elements Distribution in a Shrimp Species from Persian Gulf and Possible Role of Metallothionein in Their Redistribution During Refrigerated Storage
Nima Pourang, Ministry of Jahad-e-agriculture, Tehran, Iran
125.8 DNA Methylation and Nuclear Envelope During Cereals Germination
Lia Minasbekyan, Yerevan State University, Yerevan, Armenia
125.9 The State of the Antioxidant System in the Liver of Rats Under Experimental Hypertension Conditions
Dzmitry Miskevich, Institute of Biochemistry, Grodno, Belarus
125.10 Effects of Anti-tumor Antibiotic Daunorubicin on Histone Chromosomal Proteins
Sayeh Abdossamadi, Institute of Biochemistry & Biophysics (IBB), Tehran, Iran
125.11 Concerted Mass Spectrometry Strategies for Glycomics and Glycoproteomics
Kay-Hooi Khoo, Academia Sinica, Taipei, Taiwan
125.12 Proteomic Analysis of L6 Rat Skeletal Muscle Cells Following 6-Aminonicotinamide Treatments
In Kook Park, Dongguk University, Seoul, South Korea
125.13 Identification of CFTR Interacting Proteins and Genes Responding to CFTR Expression in Yeast
Annette Schneider, University of Pittsburgh, Pittsburgh, PA, United States
125.14 Electron Microscopy Cell Fraction Preparation Robot
Raymond Waterbury, McGill University, Montréal, QC, Canada
125.15 Re-thinking of Adleman’s Computing Model
Tao Chen, Cidmax, London, ON, Canada
125.16 Proteomic and Genomic Analyses of Androgen Response in Mouse Prostate and Liver Tissue
Eric Winstall, Centre de Recherche du CHUL, Université Laval, Québec, QC, Canada
125.17 Identification of O-GlcNAc Modified Proteins, Peptides and Their Signaling Roles in Mammalian Systems
Francina Chahal, University of British Columbia, Vancouver, BC, Canada
125.18 Heat Shock Protein Expression in Waste Incineration Workers Exposed to Dioxin
Eunil Lee, Korea University, Seoul, Republic of Korea
125.19 Analysis of Serine-/Threonine-phosphorylation Sites Via Peptide Derivatization
Detlev Suckau, Bruker Daltonics, Bremen, Germany
125.20 The Alternations in Human Bronchial Epithelial BEAS-2B Cell Proteome Upon the Treatment of Air Pollutants
Pao-chi Liao, College of Medicine, National Cheng-Kung University, Tainan, Taiwan
125.21 Post-translational Modifications of Choline Acetyltransferase
Aeri Kim, University of Western Ontario, London, ON, Canada
125.22 Design Antisense Oligonucleotide Microarrays for Genome-wide Analysis
Tao Chen, Cidmax, London, ON, Canada
125.23 Toxico Proteomic Analysis of IC-21 Cells Treated with Propanil
John Barnett, West Virginia University, Morgantown, WV, United States
125.24 Characterisation of Apolipoproteines A Phosphorylation Sites Using IMAC Affinity Column in a Gyros CD Microlaboratory
Cécile Cren-Olivé, Université des Sciences et Technologies de Lille, Villeneuve D’Ascq, France
125.25 Use of the CAPLC Q-TOF Combination for Site Specific Analysis of N-linked Glycosylation
David Heywood, Waters Corporation, ON, Canada
125.26 Directed Evolution of Cystatins-modifying Protease Inhibition
Steve Gleddie, Agriculture and Agrifood Canada, Ottawa, ON, Canada
125.27 A General Approach to the Analysis of Post-translational Modifications Combining Ion Trap Technology, Accurate Mass Detection, and Data Mining Software
Ken Miller, Thermo Finnigan, San Jose, CA, United States
125.28 Alteration of the Insulin Binding and Glucose Uptake Capability at the Hyperglycemia States
Yalkun Turakulov, Scientific Research Institute of Endocrinology, Tashkent, Uzbekistan
125.29 Semi-Pilot Scale Fermentation of Crtitic Acid by Aspergillus niger
Asad ur-Rehman, G.C. University, Lahore, Pakistan
125.30 Lack of Technical Training & Expertise in Africa
Olugbenga Balogun, B-m Communication, Llp, Accra, Ghana
125.31 The Influence of Polythylene Glycol 400 on Biochemical Structure and Function of Haptoglobin
A. Yu Nikolchenko, Institute for Problems of Cryobiology and Cryomedicine of the NAS of Ukraine, Kaharkov, Ukraine
125.32 Studies of Functions and Biochemical Mechanisms of Telomerase in Avian Marek’s Disease
Y.-J. Zhang, Changchun, University of Agriculture and Animal Sciences, Changchun, P.R. China

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