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Molecular & Cellular Proteomics 6:951-952, 2007.
© 2007 by The American Society for Biochemistry and Molecular Biology, Inc.


Professor of Physiology and Medicine, Cardiology at University of California, Los Angeles, chair of the Publications Committee of HUPO, and secretary general of HUPO.
Head of the Sequence Database Group for the European Bioinformatics Institute and president of HUPO. ¶ Professor and chair at McGill University and past president of HUPO. To whom correspondence should be addressed. E-mail: john.bergeron{at}mcgill.ca
This issue of MCP marks the progression to a new phase in the relationship between HUPO and MCP. Through the years, the support of MCP to HUPO has been mutually beneficial and, after having been the publisher for the book of abstracts for all the world congresses of HUPO (Versailles 2002, Montreal 2003, Beijing 2004, Munich 2005, Long Beach 2006), MCP now becomes the first publication to be endorsed as an official journal of HUPO.
MCP had also published a landmark editorial (Mol. Cell. Proteomics (2003) 2, 1) back in 2003, entitled "HUPO est arrivé . . .," in which Drs. Bradshaw, Burlingame, and Celis identified some of the challenges and welcomed initiatives of HUPO following its first annual world congress.
Since that time, HUPO has set up its international headquarter in Montreal. The official inauguration, which took place in October 2005, drew world renowned scientists and many other guests from the life sciences sector, business world, and international organization circles and was attended by several governmental representatives.
Currently, HUPO has an extensive membership worldwide and is coordinated through a number of committees, among them:
With respect to the HUPO initiatives, the continuum can be seen between the efforts of MCP in standardizing the reporting of mass spectrometry data for protein characterization (Carr, S., Aebersold, R., Baldwin, M., Burlingame, A., Clauser, K., and Nesvizhskii, A. Mol. Cell. Proteomics (2004) 3, 531533 and Bradshaw, R. A., Burlingame, A., Carr, S., and Aebersold, R. Mol. Cell. Proteomics (2006) 5, 787788), and the HUPO Proteomics Standards Initiatives chaired by Henning Hermjakob and co-chaired by Ruedi Aebersold and Randall Julian; the mission of the initiatives is to define community standards for data representation in proteomics to facilitate data comparison, exchange, and verification (Taylor, C. F., Hermjakob, H., Julian, R. K., Garavelli, J. S., Aebersold, R., and Apweiler, R. (2006) The Work of the Human Proteome Organisation's Proteomics Standards Initiative (HUPO PSI).OMICS 10, 145151).
Another highly publicized initiative is a two-fold effort chaired by Matthias Uhlen, with co-chairs Mike Snyder and Peter Hudson, who are putting together the Human Antibody Initiative and Protein Atlas. Two peer-reviewed publications in MCP highlight the scientific advances made by these initiatives, and ultimately these efforts will define a compendium of antibodies which are monospecific to a representative protein characteristic for each human gene product: Antibody-based proteomics for human tissue profiling (in Mol. Cell. Proteomics (2005) 4, 384393) and A human protein atlas for normal and cancer tissues based on antibody proteomics (in Mol. Cell. Proteomics (2005) 4, 19201932).
The HUPO pages in MCP will update the community on current efforts of HUPO and various scientific aspects of proteomics that HUPO is coordinating, including an education and training effort. The latter is meant to assure each HUPO member a guaranteed success in characterizing proteins via the HUPO Test Samples, itself under the umbrella of the New Resources and Technology Committee chaired by John Yates.
Moreover, the HUPO pages in MCP will be an invaluable vehicle for dissemination of information throughout the proteomics community.
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