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Submitted on May 24, 2006
Accepted on May 29, 2006

Proteomics of breast cancer: principles and potential clinical applications

François Bertucci, Daniel Birnbaum, and Anthony Gonçalves

Molecular Oncology, Institut Paoli-Calmettes, Marseille 13009

Corresponding Author: bertuccif{at}marseille.fnclcc.fr

Progresses in screening, early diagnosis, prediction of aggressiveness, of therapeutic response or toxicity, identification of new targets for therapeutic will improve survival of breast cancer. These progresses will likely be accelerated by the new proteomic techniques. In this review, we describe the different techniques currently applied to clinical samples of breast cancer and the most important results obtained with the two most popular proteomic approaches in translational research (tissue microarrays and SELDI-TOF).


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 Mol. Cell. ProteomicsHome page
A. Goncalves, E. Charafe-Jauffret, F. Bertucci, S. Audebert, Y. Toiron, B. Esterni, F. Monville, C. Tarpin, J. Jacquemier, G. Houvenaeghel, et al.
Protein Profiling of Human Breast Tumor Cells Identifies Novel Biomarkers Associated with Molecular Subtypes
Mol. Cell. Proteomics, August 1, 2008; 7(8): 1420 - 1433.
[Abstract] [Full Text] [PDF]


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