About the Cover
On the cover, when human saphenous vein is used as an arterial bypass, the vein experiences an abrupt change from the low-pressure, minimally pulsatile venous circulation to the high-pressure, pulsatile arterial circulation. The pathology of vein grafts is associated with smooth muscle cell migration and proliferation. A proteomic approach was used to investigate protein expression in contractile smooth muscle dissected from human saphenous vein both before and after exposure to arterial hemodynamics. For details, see the article by McGregor et al., pages 115–124.
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Copyright © 2008 by the American Society for Biochemistry and Molecular Biology.
