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On the cover, a ribbon diagram showing the structure of the adipocyte fatty acid binding protein (aP2) modeled with an internal 4-HNE adjacent to the reactive cysteine (117). Right image (lower) shows the MS/MS sequence data identifying cysteine 117 as the site of covalent modification, whereas the upper image depicts the feed-forward loop linking oxidative stress to lipid peroxidation and protein carbonylation. For details, see the article by Grimsrud et al., pages 624–637.
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