About the Cover
On the cover, brain region-specific variations in postsynaptic density proteins mediate distinct physiological responses to synaptic activation. Mass spectrometry analysis was used to compare both relative protein expression and phosphorylation status from proteins present in biochemical preparations of postsynaptic density from murine cortex, midbrain, cerebellum, and hippocampus. Hierarchical clustering analysis revealed that known functionally associated proteins display coordinated synaptic expression. For details, see the article by Trinidad et al., pages 684–696.
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Copyright © 2008 by the American Society for Biochemistry and Molecular Biology.
