Table III Cross-species prediction performance of Musite
TrainingTest
H. sapiensM. musculusD. melanogasterC. elegansS. cerevisiaeA. thaliana
H. sapiens0.858/43.7/15.4a0.817/35.1/9.90.782/28.7/8.20.873/43/6/13.40.813/33.5/9.30.834/38.9/16.8
M. musculus0.856/44.8/13.70.825/36.9/11.60.784/28.4/8.40.877/41.1/11.90.815/33.5/9.60.837/40.0/14.6
D. melanogaster0.850/41.3/12.20.810/30.7/9.20.815/32.6/11.30.892/47.5/18.80.815/35.3/12.30.849/45.4/15.1
C. elegans0.845/40.5/7.50.800/33.9/9.40.795/32.1/12.10.908/53.0/20.80.809/33.5/10.80.839/40.5/20.0
S. cerevisiae0.828/28.9/5.60.800/32.2/5.90.767/23.2/6.10.849/32.2/7.90.825/34.0/8.60.822/29.7/5.9
A. thaliana0.857/41.8/12.40.817/34.4/12.60.781/28.7/9.20.872/41.6/13.90.809/35.5/11.30.861/47.0/16.8
Combined0.858/44.1/14.30.819/35.9/9.40.799/31.3/10.50.886/48.5/14.90.822/36.0/11.10.839/41.1/16.8
  • a The three numbers in each cell represent the AUC, sensitivity (%) at 95% specificity, and sensitivity (%) at 99% specificity. The training model with the highest AUC for each test data set is highlighted in bold.