Table III Dynamic changes of signaling endosome components and biological processes. Biological processes enrichment was performed similarly to the disease enrichment analysis shown in Table II using a hypergeometric test and the Metacore software. Biological processes that involve transport mechanisms are highlighted in bold. GO: gene ontology. Adj.p.value: adjusted p value
GO Processes namead.p.valRatio
Cellular component organization3.24E-17158/6165
Small molecule metabolic process1.33E-1492/2752
Transport1.52E-12123/4781
Nervous system development1.66E-1291/2979
Cell projection organization2.35E-1155/1361
Cell morphogenesis involved in neuron differentiation2.61E-1139/727
Neuron development2.89E-1151/1201
Neuron projection development3.82E-1145/966
Neuron projection morphogenesis5.51E-1139/750
Cellular localization5.51E-1183/2766
Catabolic process4.63E-1069/2162
Axon development4.85E-1037/738
Brain development5.22E-1044/1016
Neuron differentiation2.13E-0953/1462
Generation of neurons4.50E-0963/1979
Sphingolipid catabolic process5.43E-099/28
Axonogenesis7.38E-0933/664
Vesicle-mediated transport9.91E-0953/1533
Membrane lipid catabolic process9.91E-099/30
Neurogenesis1.09E-0864/2081
Central nervous system development1.74E-0848/1326
Macromolecule localization2.49E-0872/2549
Secretion by cell3.07E-0832/669
Establishment of localization in cell3.10E-0867/2297
Regulation of neuron projection development4.81E-0827/497
Exocytosis1.21E-0724/415
Cellular catabolic process1.44E-0755/1766
Lysosome organization2.35E-0710/58
Lytic vacuole organization2.35E-0710/58
Neuron projection guidance2.39E-0727/541
Axon guidance2.39E-0727/541
Membrane organization4.73E-0741/1153