On the cover: Antibodies are a fundamental part of the immunity to severe malaria, but they are not well characterized. Therefore, a high-throughput peptide array technology was used to analyze the antibodies of patients against epitopes of the P. falciparum proteome. Known and novel vaccine candidates can be quickly identified. This serves as a general approach to develop vaccines and biomarkers. For details, see the article by Loeffler et al., pages 642–656.