Table III

Bacteria from which proteins were identified in the cell pellet of whole saliva

Organism name (proteinsa)Descriptionb
Bacillus halodurans (3) Produces many industrially useful alkaliphilic enzymes
Bacillus stearothermophilus (2)A thermophile widely distributed in soil, hot springs, ocean sediment and a cause of spoilage in food products
Bacillus subtilis (3)Metabolizes a wide variety of carbon sources and secretes large quantities of industrially important enzymes
B. fragilis (6)A human pathogen with the potential to severely limit the success of gastrointestinal surgery
Bdellovibrio bacteriovorus (2)Burrows into another microbe, killing it and using the remains to make offspring
Bifidobacterium longum (4) Keeps the human digestive system running smoothly
Borrelia burgdorferi (2)A spirochete that is the causative agent of Lyme disease
Buchnera aphidicola (2) Bacterial symbiont with aphids
Campylobacter jejuni (2)A food-borne pathogen that is the leading cause of food poisoning
Caulobacter crescentus (2) A model organism that is used in comparative analysis in the pathogenicity of other organisms
Clostridium acetobutylicum (3) Has the ability to convert starch into the organic solvents acetone and butanol
Clostridium tetani (3)Causes tetanus disease
Corynebacterium glutamicum (2) A natural producer of glutamic acid
E. corrodens (2)Anaerobic bacterium normally in the adult human oral cavity but that may become an opportunistic pathogen, especially in immunocompromised individuals
Escherichia coli (5)One of the foremost causes of food poisoning, also found in the human digestive tract
Haemophilus influenzae (13)An opportunistic pathogen involved in numerous diseases
Lactococcus lactis subsp. lactis (11)Used in the dairy industry for cheese, yogurt, and buttermilk production
Leifsonia xyli subsp. xyli (3) Causes ratoon stunting disease in sugarcane
Methanococcus jannaschii (3) Cannot tolerate oxygen and is one of the methane-producing microbes
Mycobacterium leprae (2)The bacterium that causes leprosy
Mycobacterium tuberculosis (2)The major cause of tuberculosis
Mycoplasma genitalium (2)Causes reproductive tract infections
P. multocida (5)A pathogenic bacteria causing many serious diseases in humans and animals
Porphyromonas gingivalis (8)One of the leading causes of periodontal disease
Rhizobium loti (2) A new species of legume root nodule bacteria
Vibrio parahaemolyticus (3) Causes food-borne gastroenteritis
Streptococcus mutans (5)A dental pathogen, is the leading cause of tooth decay worldwide
Streptococcus pneumoniae (21)Causes pneumonia, blood infections, and meningitis
Streptomyces coelicolor (3) Used to produce most of the natural antibiotics in use today
Thermoanaerobacter tengcongensis (2)A thermophile
Treponema pallidum (3)Causes syphilis
Streptococcus equisimilis [3] Can cause infections in wounds
Rhodospirillum molischianum [2] A non-sulfur purple bacteria with lamellar chromatophores
Streptococcus gordonii [2] Has been found in small numbers on the oropharyngeal mucosa and in mature supragingival plaque
  • a Number of proteins identified from the organism. Organisms shown in bold have not been reported in the literature as being detected in whole saliva. For the last three bacteria shown underlined, only a single protein was identified but from multiple different peptide sequences with the number of different peptide sequences shown in brackets.

  • b Descriptions are from the European Molecular Biology Laboratory-European Bioinformatics Institute where applicable.