Table III

Proteins with a significant (p < 0.05) change in protein level after IR between the wild type and p53K317R thymocytes

Accession numberDescriptionGene symbolWT (−IR/+IR)WT S.D.K317R (−IR/+IR)K317R S.D.p value, WT vs. K317R
NP_075631 Actin-related protein 2/3 complex, subunit 1B Arpc1b
NP_038484 Actinin α3 Actn3 3.120.511.220.250.000
NP_077175 Anaphase-promoting complex subunit 4 Anapc4 0.510.
NP_780519 Androgen-induced proliferation inhibitor Pds5b 0.300.060.960.150.029
NP_062513 NP_075679 Apoptotic chromatin condensation inducer 1 Acin1
NP_033941 Caspase 6 Casp6
NP_062414 NP_034114 Cathepsin 8, cathepsin L preproproteina0.210.020.490.100.010
NP_033980 CD3 antigen, γ polypeptide Cd3g
NP_033970 Chaperonin subunit 8 (θ ) Cct8 0.720.312.200.450.009
NP_035908 Coronin, actin-binding protein 1B Coro1b 0.270.360.770.090.008
NP_034290 CUG triplet repeat, RNA-binding protein 2 Cugbp2 0.920.185.360.670.000
NP_080120 Cysteine- and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 Chordc1 2.590.320.920.290.038
NP_444341 Eosinophil-associated, ribonuclease A family, member 6 Ear6 0.990.162.370.390.018
NP_075643 ETHE1 protein Ethe1
NP_034764 Fatty acid-binding protein 5, epidermal Fabp5 0.300.050.920.030.004
NP_031960 Glutamyl aminopeptidase Enpep
NP_038573 Hemopoietic cell phosphatase Ptpn6 6.552.000.780.150.000
NP_849209 Hydroxyacyl-coenzyme A dehydrogenase/3-ketoacyl-coenzyme A thiolase/enoyl-coenzyme A hydratase (trifunctional protein), α subunit Hadha
NP_034623 Intercellular adhesion molecule Icam1 0.330.
NP_075552 Interferon γ-inducible protein 30 Ifi30 0.650.070.300.060.021
NP_056598 Interferon α-inducible protein Isg15 1.640.240.480.080.023
NP_032548 Lactotransferrin Ltf
NP_080104 Lectin, mannose-binding 2 Lman2 0.800.136.011.300.030
NP_032720 Neutrophilic granule protein Ngp
NP_032199 Nuclear receptor subfamily 3, group C, member 1 Nr3c1
NP_036151 Peroxiredoxin 5 precursor Prdx5 0.350.070.700.090.008
NP_766283 Phospholipase A2, activating protein Plaa 0.370.050.840.140.023
NP_079826 Proteasome, 26 S, non-ATPase regulatory subunit 6 Psmd6 0.480.
NP_062648 Protein phosphatase 4, catalytic subunit Ppp4c 4.070.680.100.030.014
NP_033035 RAD21 homolog Rad21 2.640.291.300.310.016
Regulatory subunit B56, protein phosphatase 2Ab0.300.041.910.250.031
NP_080929 Replication protein A1 Rpa1 0.740.030.500.050.026
NP_033109 Ribosomal protein L30 Rpl30 3.520.441.460.210.001
NP_079863 Ribosomal protein S21 Rps21
NP_081291 Ribosomal protein S27 Rps27 7.261.482.000.630.010
NP_033120 Ribosomal protein S4, X isoform Rps4x 3.650.501.220.320.000
NP_082253 RIKEN cDNA 2310001A20 2310001A20Rik 4.640.451.050.090.002
NP_080750 SGT1, suppressor of G2 allele of SKP1 Sugt1
NP_080451 Splicing factor 3a, subunit 1 Sf3a1
NP_058622 Squamous cell carcinoma antigen recognized by T-cells 3 Sart3 0.370.
NP_613051 SR-related CTD-associated factor 6 Cherp 0.730.
NP_892035 Structure-specific recognition protein 1 Ssrp1 0.370.040.620.100.033
NP_444354 SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 5 Smarca5 0.330.050.930.180.003
NP_080784 TNF receptor-associated protein 1 Trap1 1.490.014.410.280.012
NP_035840 Tryptophanyl-tRNA synthetase Wars 0.340.040.480.060.047
NP_067497 Ubiquitin-specific protease 14 isoform 1 Usp14 1.780.020.930.110.009
  • a Unable to discriminate the two proteins.

  • b Unable to discriminate the γ, ε, δ, and β isoforms.