Table VI

Partial list of protease cleavage in the venom of B. colombiensis and C. oreganus helleri for hemorrhagic metalloproteinase HT-D and HT-C precursor (atrolysins D and C) (hemorrhagic toxins C and D)

Peptide sequencea
G↓ KITTNPSVEDHCYYR↓ G
K↓ ITTNPSVEDHCYYR↓ G
I↓ TTNPSVEDHCYYR↓ G
R↓ GRIENDADSTASISACNGLK↓ G
R↓ YIELVVVADHR↓ V
K↓ SHDNAQLLTAIELDEE↓ T
P↓ INLLMGVTMAHELGHNLGMEHDGKDCLR↓ G
L↓ MGVTMAHELGHNLGMEHDGKDCLR↓ G
M↓ GVTMAHELGHNLGMEHDGKDCLR↓ G
G↓ VTMAHELGHNLGMEHDGKDCLR↓ G
T↓ MAHELGHNLGMEHDGKDCLR↓ G
A↓ HELGHNLGMEHDGKDCLR↓ G
L↓ GHNLGMEHDGKDCLR↓ G
N↓ LGMEHDGKDCLR↓ G
G↓ MEHDGKDCLR↓ G
R↓ GASLCIMR↓ G
Y↓ KPQCILNKPLR↓ I
  • a ↓ indicates a tryptic cleavage site.