Table IV

Comparison of receiver operating characteristics from the iTRAQ ratios of the panel of the three best performing biomarkers: non-paired non-cancerous tissues give better sensitivity and specificity as a comparator than paired non-cancerous tissues

ComparisonSensitivitySpecificityPPVNPVAUC
Cancer versus paired normal0.920.830.850.920.89
Cancer versus non-paired normal0.960.960.980.900.97