Table II

Proteins reacting with autoantibodies associated to metastasis

NameLiver prevalenceLung prevalencep valueFunction
%%
Increased reactivity in liver metastasis
    PHLDB188140.0022Unknown
    AKT375140.0130Signal transduction
    PRKCH75140.0130Signal transduction
    MAPKAPK388290.0152Ras protein signal transduction
    C9orf4388290.0152Hypothetical protein
    EGFR88290.0152Signal transduction
    CAMKV63140.0455Kinase, cell signaling
    THAP363140.0455Apoptosis
    C15orf3863140.0455Hypothetical protein
    EPB41L563140.0455Cell-cell adhesion
    PGAM163140.0455Metabolism, energy pathways
    PADI463140.0455Metabolism, energy pathways
    UBE2T63140.0455Protein metabolism
    C9orf7863140.0455Hypothetical protein
    WDR6163140.0455Transcriptional regulation
    PRKCB163140.0455Signal transduction
    PRKCD63140.0455Signal transduction
    ZAP7063140.0455T cell development and activation
    ABL263140.0455Signal transduction
    WEE163140.0455Cell cycle
    DCAMKL263140.0455Unknown
    TRIM2163140.0455Transcriptional regulation
Lung prevalenceLiver prevalence
%%
Increased reactivity in lung metastasis
    PAK186130.00216Cell motility and morphology
    HOMER286250.01299Cell growth
    IRAK486250.01299Signal transduction
    PRKD286250.01299Signal transduction
    AK07548486130.01299Hypothetical protein
    C2orf1371130.01515Hypothetical protein
    PSCD371130.01515Signal transduction
    SH3BGRL271130.01515Unknown
    CDK271130.01515Cell cycle
    DAPK271130.01515Apoptosis
    TRPT186380.04545RNA-binding protein
    PDGFRB86380.04545Signal transduction
    NEK186380.04545DNA repair
    SOCS386250.04545Cytokine signaling
    EPHA486250.04545Signal transduction, angiogenesis