Table II

A. caninum protein identifications in peptide OGE

Ancylostoma accession numberMowse scoreCoverageUnique peptidesSig.aTop BLASTX hit (bit score >30)
%
Metalloprotease inhibitors
    gi|223473614284213YPutative tissue metalloprotease inhibitor Aca14 (A. caninum)
    gi|15801785015632YTissue inhibitor of metalloprotease (A. duodenale)
    gi|158018795173YPutative tissue metalloprotease inhibitor Aca14 (A. caninum)
Lysozyme-like
    gi|1579883839651YLysozyme protein 8 (C. elegans)
    gi|15800051095103FLysozyme protein 8 (C. elegans)
    gi|856729977971FLysozyme protein 7 (C. elegans)
Ancylostoma-secreted proteins
    gi|15028472309379FPlatelet inhibitor (A. caninum)
    gi|158005927149243FSecreted protein 4 precursor (A. caninum)
    gi|158007422145142FSecreted protein 4 precursor (A. caninum)
    gi|157996739119111FSecreted protein 4 precursor (A. caninum)
    gi|2912485211684YSecreted protein 4 precursor (A. caninum)
    gi|158009159108234FSecreted protein 6 precursor (A. caninum)
    gi|15800929810071FSecreted protein 6 precursor (A. caninum)
    gi|15618383198246FSecreted protein 5 precursor (A. ceylanicum)
    gi|5918947481103FSecreted protein 4 precursor (A. caninum)
    gi|592541617472FSecreted protein ASP-2 (A. ceylanicum)
    gi|15799124079184FSecreted protein 4 precursor (A. caninum)
    gi|15799754471102YSecreted protein 1 precursor (A. ceylanicum)
    gi|553918396841FSecreted protein 6 precursor (A. caninum)
    gi|1580027786871FSecreted protein 4 precursor (A. caninum)
    gi|15800922058131FSecreted protein 5 precursor (A. caninum)
    gi|1580085995092Fsecreted protein 4 precursor (A. ceylanicum)
    gi|1561837304661FSecreted protein 5 precursor (A. caninum)
    gi|15801948844284FSecreted protein 1 precursor (A. ceylanicum)
    gi|1580075804182YSecreted protein 1 precursor (A. ceylanicum)
    gi|291248563963YSecreted protein 6 precursor (A. caninum)
ES proteins of unknown function
    gi|85672966452299YExcretory/secretory protein 1 (A. ceylanicum)
    gi|21808737237304NExcretory/secretory antigen (Ostertagia ostertagi)
    gi|158012765210338NExcretory/secretory antigen (O. ostertagi)
    gi|158003804204374NExcretory/secretory antigen (O. ostertagi)
    gi|85672867194256YExcretory/secretory protein 1 (A. ceylanicum)
    gi|158006869144204FPutative ES protein F7 (O. ostertagi)
    gi|553826645871NExcretory/secretory protein 1 (A. ceylanicum)
Transthyretin-like proteins
    gi|8567296074101FTransthyretin-like protein T07C12.7 precursor (C. elegans)
    gi|15801191668232FTransthyretin-like protein 3 precursor (Radopholus similis)
    gi|15798917162233FTransthyretin-like protein 3 precursor (R. similis)
    gi|15801181249492FTransthyretin-like protein T07C12.7 precursor (C. elegans)
Lectins
    gi|158007955490348FC-type lectin family member (clec-63) (C. elegans)
    gi|158017101428337Fvon Willebrand factor type A and lectin type C domain-containing protein precursor family member (C. elegans)
    gi|157990551204175FC-type lectin family member (clec-62) (C. elegans)
    gi|1580126656771FGalectin LEC-5 (C. elegans)
    gi|1561850394172NGalectin (H. contortus)
Proteases
    gi|1431858317486NZinc metallopeptidase 1 (A. caninum)
    gi|156183344119151FAspartyl protease protein 5 (C. elegans)
    gi|1579886938381FMetalloprotease 1 precursor (A. caninum)
    gi|11000737874143YMetalloprotease-2 (A. caninum)
    gi|98495966104FCathepsin B proteinase (A. caninum)
%
    gi|15801211964123FNecpain (N. americanus)
    gi|15801202759173FCathepsin B-like proteinase (A. caninum)
    gi|15801966446122FMetalloprotease-2 (A. caninum)
Structural
    gi|85673077138187FVitellogenin structural genes protein 3 (C. elegans)
    gi|158010776100172NTetraspanin family protein (Branchiostoma belcheri tsingtaunese)
    gi|15799809210381NHistone H2B 2, putative (B. malayi)
    gi|727545792152NHistone H4 (Asterina pectinifera)
    gi|591841065362NHistone family member (his-35) (C. elegans)
Miscellaneous
    gi|158014078125384FLipid-binding protein protein 1 (C. elegans)
    gi|15801741410892FHyaluronidase 2 (Xenopus laevis)
    gi|157991384106132NFructose-bisphosphate aldolase 2 (C. elegans)
    gi|7584932101293NCytochrome c (C. elegans)
    gi|4771744093174NGlutathione S-transferase (A. caninum)
    gi|1712480286112FProtein-disulfide isomerase (A. caninum)
    gi|225324207161YFatty acid- and retinol-binding protein 2 (A. caninum)
    gi|1272757567121NAnnexin family protein 1 (C. elegans)
    gi|15800115766173NPhosphoenolpyruvate carboxykinase (Ascaris suum)
    gi|169247026692N14-3-3b protein (Meloidogyne incognita)
    gi|15618553866122NLipoamide dehydrogenase (A. suum)
    gi|1579924546582FPredicted: similar to cytochrome P450 (Monodelphis domestica)
    gi|15618451962192Nβ-Ureidopropionase (Danio rerio)
    gi|758434559293NPolyubiquitin (Bos taurus)
    gi|1692450957112NMyoglobin (Nippostrongylus brasiliensis)
    gi|15798923157152NAldehyde dehydrogenase (C. elegans)
    gi|727551354312NProbable elongation factor 1-β/1-δ 2 (C. elegans)
    gi|15798880549112Fα-2,8-Sialyltransferase (Takifugu rubripes)
Unknown function
    gi|158008118188344FHypothetical protein CBG13822 (C. briggsae)
    gi|156184318143163NHypothetical protein F46E10.10a (C. elegans)
    gi|5963011411941NNo homologous protein
    gi|596317158282NNo homologous protein
    gi|156182715106243NPredicted protein (Nematostella vectensis)
    gi|1561848878161NHypothetical protein CBG14129 (C. briggsae)
    gi|15799747666173NHypothetical protein CBG23493 (C. briggsae)
    gi|2180830362111NHypothetical protein CBG13184 (C. briggsae)
    gi|75844845572FHypothetical protein CBG13822 (C. briggsae)
    gi|169243555371FHypothetical protein C05D9.9b (C. elegans)
    gi|15801966842142NConserved hypothetical protein (A. aegypti)
  • a The presence of a signal sequence in the identified database sequence is denoted with Y, F denotes that the proteins belongs to a family of proteins containing a signal sequence, and N denotes no signal sequence.