Table II Marker phosphopeptides down-regulated by dasatinib

Underscores denote the beginning and the end of the peptide sequence in the protein sequence. pY, phosphotyrosine; pS, phosphoserine; pT, phosphothreonine.

NamePhospho positionNo. phosphositesSequenceM/LH/L
BCR1221: Ser_ASASRPQPAPADGADPPPAEEPEARPDGEGpSPGK_0.30.2
6441: Tyr_NSLETLLpYKPVDR_0.30.1
ABL1805, 8082: Ser, Ser_DIMEpSpSPGSSPPNLTPK_0.40.4
2481: Ser_NKPTVYGVpSPNYDK_0.60.4
2451: Tyra_NKPTVpYGVSPNYDK_0.40.4
SRC4261: Tyra_LIEDNEpYTAR_0.40.1
MAPK1185, 1872: Thr, Tyra_VADPDHDHTGFLpTEpYVATR_0.10.1
MAPK3202, 2042: Thr, Tyra_IADPEHDHTGFLpTEpYVATR_0.10.1
MYC621: Ser_KFELLPTPPLpSPSR_0.40.2
LYN5781: Tyr_AEERPTFDYLQSVLDDFYTATEGQpYQQQP_0.30.3
  • a Autophosphorylation sites.