Table I

Identified proteins previously examined as ovarian cancer biomarkers

Protein nameaMolecular massRefs.
Da
AFM, afamin precursor69,052 36
CHI3L1, chitinase-3-like protein 1 precursor (YKL-40)42,609 37
CLEC3B, hypothetical protein DKFZp686H17246 (tetranectin)17,77638, 39
KLK10, kallikrein-10 precursor30,12040, 41
KLK11, isoform 1 of kallikrein-11 precursor27,448 42
KLK6, kallikrein-6 precursor26,838 43
KLK7, isoform 1 of kallikrein-7 precursor27,507 44
KLK9; KLK8, isoform 1 of neuropsin precursor28,029 45
LCN2, neutrophil gelatinase-associated lipocalin precursor22,571 46
LGALS1, galectin-114,69847, 48
MMP2, 72-kDa type IV collagenase precursor73,86749–51
PEBP1, phosphatidylethanolamine-binding protein 121,039 52
PLAUR, isoform 1 of urokinase plasminogen activator surface receptor precursor36,95938, 53, 54
RBP4, plasma retinol-binding protein precursor22,992 55
SERPINA3, isoform 1 of α1-antichymotrypsin precursor50,583 34
SERPINE1, plasminogen activator inhibitor 1 precursor45,042 56
SERPINF2, α2-antiplasmin precursor55,047 57
SPP1, isoform A of osteopontin precursor35,40558–60
TF, serotransferrin precursor77,03261, 62
THBS1, thrombospondin-1 precursor129,36463, 64
TIMP1, metalloproteinase inhibitor 1 precursor23,153 65
TIMP2, metalloproteinase inhibitor 2 precursor24,382 51
TMEM110; ITIH4, isoform 1 of inter-α-trypsin inhibitor heavy chain H4 precursor103,308 65
TTR, transthyretin precursor15,86935, 55, 56, 62
WFDC2, isoform 1 of whey acidic protein four-disulfide core domain protein 2 precursor12,97459, 66, 67
  • a For protein IPI accession numbers, see supplemental Table 1.