Table I

Proteomics comparisons of ApcMin+/− adenoma and top and bottom of crypts

The WFCCM was used to select the statistically significant peaks that allowed the classification of the three groups of samples. The classification accuracies were calculated using the leave-one-out cross-validation classification methods. CI, confidence interval.

Classification (no. of spectra)Number of differentially expressed peaksClassification accuracy (95% CI)pvalue
%
Top (74) vs. bottom of normal crypts (65)1471 (64, 79)<0.0001
Adenoma (86) vs. top of normal crypt (74)6899 (98, 100)<0.0001
Adenoma (86) vs. bottom of normal crypts (65)43100 (100, 100)<0.0001