Table II c-statistics for CEP markers

The c-statistic and 95% CI were determined by a logistic regression model fitted with log-transformed CEP adduct concentration and autoantibody titer as independent variables and were validated by bootstrap resampling and 10-fold cross-validation.

nTotalBootstrap validationCross-validation
Estimate95% CIEstimate95% CIEstimate95% CI
Control488
All AMD9160.760.73, 0.790.760.73, 0.790.760.73, 0.78
AMD category 21770.760.72, 0.800.760.72, 0.800.750.71, 0.79
AMD category 31300.730.68, 0.770.730.69, 0.780.720.68, 0.77
AMD category 46090.770.74, 0.800.770.74, 0.800.770.74, 0.80