Table I O-GlcNAc sites identified using ETD mass spectrometry

O-GlcNAc sites are bold with a lowercase g preceding the residue. M(ox), oxidized methionine.

ProteinGI numberPeptide sequenceO-GlcNAc site(s)Novel?
Tau517394331VVgSGDTSPR339Ser711Yes
α-Synuclein14903705861EQVTNVGGAVVgTGVTAVAQK80Thr72Yes
γ-Synuclein12206626159TKEQANAVgSEAVVSSVNTVATK80Ser67Yes
β-Synucleina7740421524QGVgTEAAEK32Thr27Yes
Host cell factor C12133853151147IgTVAPGALER1156Thr1148Yes
Methyl-CpG-binding protein 2149029883434VAAAAgTTTTTTTTTVAEK455Thr443Yes
434gTQPM(ox)VAAAAg(TT)TTTTTTTVAEK455Thr334, Thr443 (or Thr444)Yes
430EPAKgTQPM(ox)VAAAAg(TT)TTTTTTTVAEK455Thr334, Thr443 (or Thr444)Yes
Spectrin β21490448562310HDTSASTQSTPASgSR2324Ser2323No4
  • a The same peptide is also in γ-synuclein.