Table II Relative -fold changes for selected proteins that were identified by 2D DIGE/MS and/or by network analysis as determined by confirmational immunoblot analysis
ProteinsSTZ-induced diabetic/controla
1 week2 months
Hsp47−2.8 ± 0.0013−∞ ± 0.0197
p53b1.20 ± 0.041.50 ± 0.013
14-3-3-γ1.68 ± 0.00171.57 ± 0.0027
HDAC1b1.29 ± 0.081.16 ± 0.031
MPZ1.08 ± 0.111.17 ± 0.14
β-Actin1.01 ± 0.01241.08 ± 0.0373
  • a Average of immunoblots from two independent biological replicates of STZ-induced diabetic rat model or age-matched control.

  • b Selected proteins that were identified by the network analysis.