Table IV Comparison of peptide sequences identified in TXP immunoaffinity enriched fractions versus peptide sequences found in empirical databases representing the subset of tryptic peptides experimentally shown to be detectable by mass spectrometry

Immunoaffinity enriched fractions are in bold type. Protein abundance in human plasma is indicated where known. NK, not known.

SequenceMolecular mass, DaUniprot referenceProtein Atlas Human PlasmaHUPO Plasma Proteome ProjectPlasma concentration, μg/mlReference
VLLDQLR855.52Q9HDC9: Adipocyte plasma membrane-associated proteinIPI00031131.2NK
VLLDGVQNPR1109.62P01024: Complement C3PAp00028461IPI00164623.21.3E+0338
VLLDQLGTTISFER1590.86P04114: Apolipoprotein B-100PAp00028462IPI00022229.19.15E+0239
VLLDWINDVLVEER1711.91Q9HBI1: β-ParvinPAp00139400NK
VELEDWNGR1116.52P02679: Fibrinogen γ chainPAp00045733IPI00021891.39.15E+0239
VELEDFNGNR1191.55O75636: Ficolin-3IPI00293925.11.5E+0144
VELEDWAGNEAYAEYHFR2197.97P02671: Fibrinogen α chainPAp001494571.25E+0339
GDVAFVK734.40P02787: SerotransferrinPAp00161845IPI00022463.14.00E+0345
DGAGDVAFVK977.48P02787: SerotransferrinPAp00024622IPI00022463.14.00E+0345
QPSSAFAAFVK1151.60P01024: Complement C3PAp00027449IPI00032257.1
IPI00164623.2
1.3E+0338
CLAEGAGDVAFVK1335.63P08582: MelanotransferrinPAp00001121NK
CLAENAGDVAFVK1392.65P02788: LactotransferrinPAp000644862.70E-0145
DAVEKPQEFTIVAFVK1819.97P04114: Apolipoprotein B-100PAp00024585IPI00022229.19.15E+0244
IYHSHIDAPK1179.60P00450: CeruloplasminPAp00044520IPI00017601.12.80E+0238
FFQYDTWK1133.52P01344: Insulin-like growth factor IIPAp001374044.00E-0145
HRPELIDYGK1226.64P12814: α-Actinin 1PAp00040808NK
EPCVESLVSQYFQTVTDYGK2349.06P02652: Apolipoprotein A-IIPAp00024985IPI00021854.12.44E+0238
VVCSCTEGYR1229.47P00740: Coagulation factor IXPAp00378430IPI00296176.14.50E+0048
DDGSWEVIEGYR1424.62P00367: Glutamate dehydrogenase 1, mitochondrialPAp00064702NK
P49448: Glutamate dehydrogenase 2, mitochondrialNK
MDCQECPEGYR1443.48P21333: Filamin-APAp000268273.50E-0240
NIPGDFECECPEGYR1841.69P07225: Vitamin K-dependent protein SIPI00294004.12.50E+0139
MMHEEHLR1081.48Q8IY82: Coiled-coil domain-containing protein 135IPI00217687.1NK
VVNSTTGPGEHLR1365.70P07996: Thrombospondin-1PAp004158752.00E-0145
SCVGETTESTQCEDEELEHLR2508.00P10643: Complement component C7PAp00027646IPI00296608.1
APTAQVESFR1104.56P24821: TenascinPAp000919211.00E+0045
APEENTAAIVYVENGESENQESFR2682.20Q8TEP8: Centrosomal protein of 192 kDaIPI00181475.1NK
TDMELEVLR1104.55P12955: Xaa-Pro dipeptidasePAp00094413IPI00257882.1NK
FLEEHPGGEEVLR1510.74P00167: Cytochrome b5PAp00185870NK
LLNYNPEDPPGSEVLR1811.91Q15166: Serum paraoxonase/lactonase 3PAp00093392IPI00217446.1NK
IFFYDSENPPASEVLR1882.91P27169: Serum paraoxonase/arylesterase 1PAp00025909IPI00218732.15.93E+0138
MEGDSVLLEVDGEEVLR1888.91P04278: Sex hormone-binding globulinPAp00044875IPI00023019.16.00E+0044
YNPVVIDFEMQPIHEVLR2198.12P07357: Complement component C8 alpha chainPAp00039195IPI00011252.14.70E+0139
TPSCGDICNFPPK1491.61P04003: C4b-binding protein α chainPAp00060583IPI00021727.13.65E+0239
EASHVLEVK1010.54Q9Y5S2: Serine/threonine-protein kinase MRCK βIPI00005689.2NK
IDDIWNLEVK1243.64P04114: Apolipoprotein B-100PAp00025874IPI00022229.19.15E+0244
ALEEANADLEVK1300.65P13646: Keratin, type I cytoskeletal 13PAp00039444IPI00179358.1NK
P02533: Keratin, type I cytoskeletal 14IPI00218819.1NK
P19012: Keratin, type I cytoskeletal 15NK
P08779: Keratin, type I cytoskeletal 16NK
ALEEANTELEVK1344.68Q04695: Keratin, type I cytoskeletal 17PAp00032389IPI00244103.1NK
VFGAPEVLENLEVK1542.83Q8TEM1: Nuclear pore membrane glycoprotein 210IPI00291755.1NK
LSQSGEVGEPAGTDPGLDDLDVALSNLEVK3024.48Q86UX7: Fermitin family homolog 3PAp00074141NK
GLPAPIEK823.48P01859: Ig γ2 chain C regionPAp00062066IPI00004608.12.84E+0339
ALPAPIEK837.50P01857: Ig γ1 chain C region;PAp00029028IPI00004617.14.30E+0339
P01860: Ig γ3 chain C regionIPI00152302.1NK
IPI00168728.1
DAGMQLQGYR1137.52P00505: Aspartate aminotransferase, mitochondrialPAp00131640NK
TDGCQHFCLPGQESYTCSCAQGYR2881.05P22891: Vitamin K-dependent protein ZPAp00445892IPI00027843.13.00E+0044
VPQVSTPTLVEVSR1510.84P02768: serum albuminPAp00028510IPI00022434.14.10E+0438
LFDSDPITVTVPVEVSR1872.98P10909: ClusterinPAp00026453IPI00291262.11.0E+0239