Table II Proteins with significantly increased resistant:sensitive protein ratios in BT474
Uniprot IDProtein nameProtein descriptionRatio (BT474R:BT474)P value
Q9UQ80EBP1/PA2G4ErbB-3 binding protein 1/proliferation-associated protein 2G413.61.71 × 10−20
Q86UY5FAM83AProtein FAM83A9.78.69 × 10−16
O43281EFSEmbryonal Fyn-associated substrate8.21.02 × 10−13
P00533EGFREpidermal growth factor receptor7.23.34 × 10−12
Q86V48LUZP1Leucine zipper protein 14.19.71 × 10−7
Q9HD67MYO10Myosin-X11.81.05 × 10−6
Q59EG8Q59EG8Proteasome 26S non-ATPase subunit 2 variant12.21.83 × 10−6
P11413G6PDGlucose-6-phosphate 1-dehydrogenase3.92.38 × 10−6
P80723BASP1Brain acid soluble protein 111.53.11 × 10−6
P58107EPPK1Epiplakin3.83.23 × 10−6
Q5T9W8Q5T9W8Heat shock protein 90kDa alpha (cytosolic), class B member 110.43.86 × 10−6
Q9NZT1CALML5Calmodulin-like protein 53.84.03 × 10−6
P98088MUC5AMucin-5AC (fragments)9.58.85 × 10−6
P37268FDFT1Squalene synthetase3.32.82 × 10−5
Q9BVG4CXorf26UPF0368 protein Cxorf263.18.47 × 10−5
A8MXZ4GPRC5CPutative uncharacterized protein GPRC5C3.11.05 × 10−4
P10909CLUClusterin3.11.10 × 10−4
A8K5P3A8K5P3Zinc finger protein 74 (Cos52)7.01.88 × 10−4
A7Y9J9A7Y9J9Mucin 5AC, oligomeric mucus/gel-forming6.63.19 × 10−4
P21291CSRP1Cysteine and glycine-rich protein 15.95.00 × 10−4
P45954ACADSBShort/branched chain specific acyl-CoA dehydrogenase, mitochondrial2.75.50 × 10−4
Q07065CKAP4Cytoskeleton-associated protein 46.05.99 × 10−4
Q59G88Q59G88Putative uncharacterized protein5.76.68 × 10−4
P01034CYTCCystatin-C5.01.81 × 10−3
Q9ULT8HECD1E3 ubiquitin-protein ligase HECTD14.92.06 × 10−3
Q99536VAT1Synaptic vesicle membrane protein VAT-1 homolog4.72.54 × 10−3
O15551CLD3Claudin-34.44.25 × 10−3
P22307SCP2Non-specific lipid-transfer protein2.34.36 × 10−3
Q9Y3L5RAP2CRas-related protein Rap-2c4.44.67 × 10−3
Q8N1F7NUP93Nuclear pore complex protein Nup934.35.18 × 10−3
P15941MUC1Mucin-14.35.48 × 10−3
P09543CNP2′,3′-cyclic-nucleotide 3′-phosphodiesterase2.26.52 × 10−3
O75487GPC4Glypican-44.17.11 × 10−3
Q9BTI6Q9BTI6FLOT2 protein4.08.17 × 10−3
P24593IBP5Insulin-like growth factor-binding protein 53.99.09 × 10−3
B4E2S3B4E2S3cDNA FLJ565613.81.05 × 10−2
Q8N357C2orf18Transmembrane protein C2orf182.11.12 × 10−2
O95831AIFM1Apoptosis-inducing factor 1, mitochondrial2.11.18 × 10−2
P67936TPM4Tropomyosin alpha-4 chain2.01.81 × 10−2
B4DMN1B4DMN1Ras-related protein Rab-11A3.41.82 × 10−2
P31150GDIARab GDP dissociation inhibitor alpha3.41.84 × 10−2
B1ANH3B1ANH3Guanylate kinase 13.42.02 × 10−2
Q9Y4L1HYOU1Hypoxia up-regulated protein 12.02.22 × 10−2
Q14764MVPMajor vault protein3.32.40 × 10−2
B9ZVM9B9ZVM9Putative uncharacterized protein TCP10L23.32.55 × 10−2
P00558PGK1Phosphoglycerate kinase 11.92.60 × 10−2
P55084HADHBTrifunctional enzyme subunit beta, mitochondrial1.92.95 × 10−2
Q14395Q14395Mucin (fragment)3.13.45 × 10−2
Q6W4X9MUC6Mucin-63.03.49 × 10−2
A0MZ66SHOT1Shootin-13.03.53 × 10−2
Q4JM47Q4JM47AGR23.03.82 × 10−2
O14745SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF11.84.13 × 10−2
Q8WXQ7Q8WXQ7Propionyl coenzyme A carboxylase, alpha polypeptide2.84.70 × 10−2
B7Z2Z4B7Z2Z4Propionyl-CoA carboxylase beta chain, mitochondrial2.94.83 × 10−2
O75223GGCTGamma-glutamylcyclotransferase2.94.92 × 10−2