Table I Significantly changed proteins post–EGF exposure; proteins identified with significant changes following EGF treatment at at least two time points over a 12 to 48 h time course, p < 0.05
Accession numberProtein name12 h EGF24 h EGF48 h EGF
117553627Acetylserotonin O-methyltransferase-like1.623.151.62
210147571Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E0.570.45N/A
4501867Aconitase 2, mitochondrialN/A0.370.58
24308338Actin filament associated protein 1-like 20.540.56N/A
4557251ADAM metallopeptidase domain 101.76N/A2.19
4502227ADP-ribosylation factor-like 10.660.65N/A
4506797Ataxin 70.630.66N/A
41281429Basic leucine zipper and W2 domains 1 pseudogene 1; basic leucine zipper and W2 domains 1 like 1; basic leucine zipper and W2 domains 12.283.80N/A
51599156Chromodomain helicase DNA binding protein 41.601.71N/A
41281603Chromosome 19 open reading frame 330.480.26N/A
221316630Coatomer protein complex, subunit beta 11.851.52N/A
21070976Diablo homologN/A1.541.50
6912328Dimethylargininedimethylaminohydrolase 13.59N/A6.02
24430135Dolichyl-phosphate mannosyltransferase polypeptide 31.52N/A1.52
18426915Drebrin 11.77N/A1.83
166362728Epidermal growth factor1.71N/A2.65
5031711Eukaryotic translation initiation factor 1B1.521.61N/A
151108473Fission 1 (mitochondrial outer membrane) homologN/A0.591.54
17149836FK506 binding protein 1A, 12 kDa1.722.41N/A
194018522G1 to S phase transition 11.511.61N/A
4758442Glia maturation factor, beta0.622.04N/A
20127446Integrin, beta 52.080.48N/A
112380628Lysosomal-associated membrane protein 1N/A1.840.41
4504957Lysosomal-associated membrane protein 20.65N/A0.44
54873600Mesencephalic astrocyte-derived neurotrophic factor2.73N/A0.46
32483374NOP56 ribonucleoprotein homolog2.161.712.57
7706254NOP58 ribonucleoprotein homolog1.901.821.71
56118310Nuclear casein kinase and cyclin-dependent kinase substrate 10.640.62N/A
7662018PHD finger protein 33.242.49N/A
21735598Programmed cell death 4 (neoplastic transformation inhibitor)0.64N/A0.56
124494254Proliferation-associated 2G4, 38 kDa; proliferation-associated 2G4 pseudogene 41.88N/A1.67
13376751Proteasomal ATPase-associated factor 11.68N/A1.70
44680114Proteasome (prosome, macropain) assembly chaperone 11.581.80N/A
94429050SEC22 vesicle trafficking protein homolog B1.561.73N/A
115583685Solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
25777713S-phase kinase-associated protein 11.801.89N/A
224493972Thioredoxin domain containing 5 (endoplasmic reticulum); muted homolog1.631.82N/A
218931148Tropomodulin 2 (neuronal)0.53N/A0.52
34098946Y box binding protein 1N/A2.090.66