Table II Selected cancer-associated proteins

The proteins were selected based on their association with different cancer types, and references to the associations are provided in the table. The table provides information about the protein concentration in plasma and the reported and the measured trend in fold change of the selected proteins comparing cancer versus normal conditions (↑ = higher protein abundance in cancer specimens and ↓ = lower protein abundance in cancer specimens).

Gene nameDescriptionPlasma concentrations (μg/ml) (40, 48, 49)Reported trend cancer versus normalMeasured trend by SRM cancer versus normalRefs.
AHSGα-2-HS-glycoprotein (Fetuin-A)8050
APOBApolipoprotein B-1007205153
CD44Extracellular matrix receptor III) (hyaluronate receptor)223-5457
CLUClusterin56↓↑50, 5862
F11Coagulation factor XI566
HPHaptoglobin88050, 65, 70
PON1Serum paraoxonase/aryl esterase 18958, 71, 72
SERPINA3α-1-Antichymotrypsin45073, 75
SERPINA6Corticosteroid-binding globulin7076
SERPINA7Thyroxine-binding globulin1977
TIMP1Tissue inhibitor of metalloproteinases 1957880