Table I Relationship between CRKL and FLT1 expression and clinicopathological factors in 192 HCC patients
CharacteristicsCRKL expressionFLT1 expression
LowHighp valueaLowHighp valuea
(n = 81)(n = 111)(n = 81)(n = 111)
Age0.6940.759
    Years (mean ± S.D.)61.19 ± 12.5361.77 ± 11.6161.95 ± 11.1561.21 ± 11.9
Gender0.2690.502
    Male73947295
    Female817916
AFPc0.1630.079
    <400 ng/ml68846983
    ≥400 ng/ml13271228
Stage0.4320.432
    I + II59755975
    III22362236
Hepatitis B virus0.5070.058
    Negative30363432
    Positive51754779
Hepatitis C virus0.9750.049b
    Negative60825488
    Positive21292723
Recurrence status0.0890.316
    No23202122
    Yes58916089
Major vessel invasion0.0960.224
    No75947495
    Yes617716
  • a p value for age was derived from Student's t test; other p values were derived with a two-tailed Pearson χ2 test. S.D. represents standard deviation.

  • b p < 0.05.

  • c AFP represents α-fetoprotein.