Table II Ingenuity pathway analysis-predicted top biological functions
Top biological functionsp values (ranging from)aNo. of moleculesb
Diseases and disorders
    Cancer9.44E-08 to 2.87E-0272
    Gastrointestinal disease9.44E-08 to 2.58E-0241
    Neurological disease1.10E-06 to 2.56E-0242
    Psychological disease1.10E-06 to 1.72E-0220
    Dermatological diseases and conditions2.57E-05 to 2.84E-0230
Molecular and cellular functions
    Cellular movement6.94E-07 to 2.56E-0243
    Cell death7.97E-06 to 2.90E-0261
    Cell morphology8.87E-06 to 2.91E-0231
    Cellular assembly and organization8.87E-06 to 2.57E-0231
    Nucleic acid metabolism7.19E-05 to 2.56E-027
Physiological system development and function
    Renal and urological system development and function1.55E-04 to 2.04E-0213
    Organ morphology1.55E-04 to 2.04E-0229
    Tissue development2.58E-04 to 2.04E-0242
    Tumor morphology2.58E-04 to 2.54E-0211
    Cardiovascular system development and function2.58E-04 to 2.54E-0221
  • a Fisher's exact test was used to calculate a p value for each protein of the dataset identified in the biological function studied, indicating the probability that each biological function assigned to the data set is assigned by chance; then we have a range of p values corresponding to all p values calculated for all proteins of the dataset in the biological function.

  • b The number of molecules of the 155 differentially released protein dataset is shown.