Table II Functional classification of the significantly altered proteins from CacyBP-KD dataset. These proteins have met the criteria (i.e. unused protein score > 1.3 and change in expression level of at least 1.57 fold for SW620-CacyBP KD vs. SW620-Scr Control cell) as defined in the “materials and method” as well as “results” section
Unused Protein score% Sequence CoverageAccession NumberNameSpeciesPeptides (95%)Expression patterniTRAQ Ratio (Mean± S.E.)
Proteins involved in Cell proliferation
    430.6IPI00011590.1Fos-related antigen 1960622.07 ± 0.25
    29.5IPI00013895.1S100A11 Protein960611.72 ± 0.16
Proteins involved in focal adhesion
    2.2637.7IPI00018451.6Calcium and integrin-binding protein 1960611.70 ± 0.11
    617.8IPI00029834.3Isoform 1 of Rhotekin960630.31 ± 0.04
    4.0113.4IPI00014068.1Isoform 1 of Serine/threonine-protein kinase PAK 4960630.62 ± 0.07
Proteins involved in cytoskeleton organization
    660.6IPI00791316.1Neuromodulin isoform 1960632.63 ± 0.25
    97.3768.8IPI00396171.4Isoform 1 of Microtubule-associated protein 49606741.63 ± 0.05
    27.558.2IPI00000861.1Isoform 1 of LIM and SH3 domain protein 19606361.60 ± 0.04
Proteins involved in integrin internalization
    11.3923.5IPI00011285.1Calpain-1 catalytic subunit960670.61 ± 0.07
    8.8925.9IPI00556059.1Isoform 2 of Chromosome-associated kinesin KIF4A960660.37 ± 0.05