Table I Proteins with increased abundance during normal growth
Identified proteinsAccession no.Molecular massFisher's exact test (p value)Normal NSAFHypoxic NSAFaLog fold change
Polyphosphate kinase, PpkRv298483 kDa(0.0000)6616.04
Phosphoglycerate kinase, PgkRv143743 kDa(0.0000)5724.83
Acyl-CoA dehydrogenase, FadE4Rv023163 kDa(0.0002)2314.52
DehydrogenaseRv3389c30 kDa(0.0010)1914.25
19-kDa lipoprotein antigen precursor, LpqHRv376315 kDa(0.0021)1714.09
Immunogenic protein, Mpt64Rv1980c25 kDa(0.0021)1714.09
Hypothetical proteinRv2319c32 kDa(0.0021)1714.09
Aminomethyltransferase, GcvTRv2211c40 kDa(0.0021)1714.09
Superoxide dismutase sodaRv384623 kDa(0.0031)1614.00
Cysteinyl-tRNA synthetase 1, CysS1Rv3580c52 kDa(0.0031)1614.00
DNA polymerase I, PolARv162998 kDa(0.0031)1614.00
Transmembrane serine/threonine-protein kinase E, PknERv174361 kDa(0.0031)1614.00
Iron-regulated short-chain dehydrogenase/reductaseRv322430 kDa(0.0006)2623.70
Fatty-acid-CoA ligase, FadD23Rv382663 kDa(0.0099)1313.70
Leucyl-tRNA synthetase, LeuSRv0041108 kDa(0.0150)1213.58
Pyridoxamine 5-phosphate oxidase, PdxHRv260725 kDa(0.0150)1213.58
Conserved hypothetical proteinRv2624c29 kDa(0.0002)3433.50
Aldehyde dehydrogenaseRv045855 kDa(0.0066)1923.25
Acetyl-/propionyl-CoA carboxylase α subunit, AccA1Rv2501c71 kDa(0.0001)4553.17
Fatty-acid-CoA ligase, FadD7Rv011955 kDa(0.0020)2733.17
Electron transfer flavoprotein β subunit, FixARv3029c28 kDa(0.0020)2733.17
Fatty-acid-CoA ligase, FadD36Rv119350 kDa(0.0460)913.17
TransferaseRv1201c33 kDa(0.0460)913.17
Phosphoribosylamine-glycine ligase, PurDRv077244 kDa(0.0028)2633.12
Pyruvate kinase, PykARv161751 kDa(0.0021)3142.95
Low molecular weight protein antigen, Cfp2Rv2376c17 kDa(0.0250)1522.91
Glutamyl-tRNARv3009c55 kDa(0.0000)83122.79
Transmembrane serine/threonine-protein kinase H, PknHRv1266c67 kDa(0.0036)3352.72
Conserved alanine-rich proteinRv2744c29 kDa(0.0480)1322.70
Transmembrane serine/threonine-protein kinase D, PknDRv0931c70 kDa(0.0005)5182.67
Conserved hypothetical proteinRv2159c36 kDa(0.0320)1832.58
ATP-dependent protease ATP-binding subunit, ClpC1Rv3596c94 kDa(0.0000)181322.50
Glutamine synthetase, GlnA2Rv2222c50 kDa(0.0280)2242.46
30 S ribosomal protein S1, RpsARv163053 kDa(0.0360)2142.39
Succinyl-CoA synthetase β chain, SucCRv095141 kDa(0.0170)4092.15
Endopeptidase ATP-binding protein chain B, ClpBRv0384c93 kDa(0.0003)131331.99
Glutamine synthetase, GlnA1Rv222054 kDa(0.0200)65181.85
10-kDa chaperonin, GroESRv3418c11 kDa(0.0049)136411.73
  • a A value of 1 indicates an NSAF of 0.