SLAC^{a} | FEL^{b} | REL^{c} | Integrative | MEME Sites^{d} | PAML^{g} | ||||
---|---|---|---|---|---|---|---|---|---|

SLAC + FEL + REL + MEME | M8 | M2a | Clade Model C (ω)^{h} | ||||||

Iguania, Varanidae and Crotalinae β-Defensin | |||||||||

ω>1^{e} | 0 | 1 | 0 | 1 | 1 | ||||

Iguania | ω<1^{f} | 3 | 9 | 9 | 14 | 0 | (0 + 1) | 0 | 3.61^{sig} |

ω = | 0.43 | – | 0.59 | – | 0.70 | 0.77 | |||

ω>1^{e} | 0 | 0 | 12 | 13 | 14 | 12 | |||

Crotalinae | ω<1^{f} | 1 | 0 | 0 | 1 | 2 | (6 + 8) | (6 + 6) | 4.43^{sig} |

ω = | 1.42 | – | 4.03 | – | 3.23 | 3.22 | |||

ω>1^{e} | 0 | 0 | 0 | 1 | |||||

Varanidae | ω<1^{f} | 0 | 5 | 14 | 14 | 1 | 0 | 0 | 1.97^{sig} |

ω = | 1.10 | – | – | – | 1.31 | 1.31 | |||

Iguania and Homalopsidae Veficolins | |||||||||

ω>1^{e} | 0 | 1 | 10 | 17 | 1 | 1 | |||

Iguania | ω<1^{f} | 11 | 35 | 80 | 85 | 8 | (1 + 0) | (0 + 1) | 0.33^{sig} |

ω = | 0.52 | – | – | – | 0.49 | 0.49 | |||

ω>1^{e} | 0 | 0 | 0 | 3 | 24 | 14 | |||

Homalopsidae | ω<1^{f} | 2 | 5 | 34 | 34 | 3 | (8 + 16) | (2 + 12) | 3.06^{sig} |

ω = | 0.86 | – | – | – | 1.12 | 1.12 | |||

Anguimorpha and Caenophidia CRiSPs | |||||||||

ω>1^{e} | 1 | 3 | 16 | 28 | 4 | 4 | |||

Anguimorpha | ω<1^{f} | 21 | 38 | 100 | 102 | 10 | (2 + 2) | (2 + 2) | 2.04^{sig} |

ω = | 0.56 | – | 0.77 | – | 0.70 | 0.83 | |||

ω>1^{e} | 3 | 13 | 62 | 67 | 17 | 26 | |||

Caenophidia | ω<1^{f} | 7 | 19 | 50 | 59 | 24 | (8 + 9) | (17 + 9) | 3.94^{sig} |

ω = | 1.15 | – | 4.13 | – | 1.21 | 1.21 |

↵

^{a}Single Likelihood Ancestor Counting.↵

^{b}Fixed-effects likelihood.↵

^{c}Random-effects likelihood.↵

^{d}Sites detected as experiencing episodic diversifying selection (0.05 significance) by the Mixed Effects Model Evolution (MEME).↵

^{e}Number of positively selected sites at 0.05 significance (for SLAC, FEL) or 50 Bayes factor (for REL).↵

^{f}Number of negatively selected sites at 0.05 significance (for SLAC, FEL) or 50 Bayes factor (for REL).↵

^{g}Positively selected sites detected using the Bayes Empirical Bayes approach implemented in the site models (M8 and M2a). Sites detected at 0.99 and 0.95 significance are indicated in the parenthesis.↵

^{h}Mean dN/dS computed by the Clade Model C analysis for Iguania versus Crotalinae crotamines and Iguania versus Colubridae veficolins; ω: mean dN/dS; sig: Clade Model C analysis significant at 0.001.