Table II Epithelium IHC scoring of NAAA and PTK7. Immunohistochemical staining was performed for N-acylethanolamine acid amidase (NAAA) and protein tyrosine kinase 7 (PTK7) on tissue microarray (TMA) with 56 cases of prostate cancer tissues. From each case, four cores of tumor tissues and two cores of adjacent normal prostate tissues were included in the TMA. The numbers of cases with pathologist-read epithelium IHC scores of 0, 1, 2, and 3 are listed for adjacent normal tissue and tumor tissues with a Gleason score less than or equal to 3 + 4 and more than or equal to 4 + 3 for both NAAA and PTK7
Epithelium IHC scoreNAAAPTK7
01230123
Adjacent normal22 (39.3%)20 (35.7%)9 (16.1%)5 (8.9%)38 (67.9%)15 (26.8%)3 (5.4%)0 (0%)
Gleason score ≤ 3 + 40 (0%)3 (12%)8 (32%)14 (56%)10 (40%)8 (32%)6 (24%)1 (4%)
Gleason Score ≥ 4 + 36 (19.4%)8 (25.8%)10 (32.3%)7 (22.6%)2 (6.5%)17 (54.8%)8 (25.8%)4 (12.9%)