Table V ERAP1 susceptibility of N-terminal residues selectively found among HLA-B27 subtypes with differential AS association or thermostability. The data represent the mean frequency (%) of residues with trimming susceptibility scores <10 (resistant), >50 (susceptible), and the resistant/susceptible ratio among the peptides selectively found among the AS-associated, non-AS-associated, high thermostability, low thermostability subtypes, and the corresponding subsets of peptides ≤9-mers. The ratios reflecting an increased frequency of resistant vs. susceptible residues are highlighted in boldface
NaResistant (%)Susceptible (%)Ratio
AS association
    AS-associated116728.419.41.5
    ≤9-mers61630.816.11.9
    Non-AS associated22719.423.30.8
    ≤9-mers19117.324.10.7
Thermostability
    High98829.719.31.5
    ≤9-mers52632.316.91.9
    Low31318.522.70.8
    ≤9-mers24418.022.50.8
  • a Number of peptides (7- to 15-mers).