Table VII PKD2 substrate candidates phosphosites. List of phosphosites from selected PKD2 substrate candidates, presented as gene name, protein name, modified position (Mod. Pos.) and SILAC ratio KO/WT (KO/WT ratio, averaged value of the three biological replicates)
Gene nameProtein nameMod. Pos.KO/WT Ratio
Akap10A-kinase anchor protein 10, mitochondrialS2570.47
Arhgap11aRho GTPase-activating protein 11AS8470.51
Arhgef2Rho guanine nucleotide exchange factor 2S7180.57
Arid4bAT-rich interactive domain-containing protein 4BS4730.42
Arid5bAT-rich interactive domain-containing protein 5BS10020.20
Bud13BUD13 homologS180.39
Casp8ap2CASP8-associated protein 2S12200.48
CblE3 ubiquitin-protein ligase CBLS6170.57
Ccdc92Coiled-coil domain-containing protein 92S3080.40
Dcaf5DDB1- and CUL4-associated factor 5S7900.11
Dennd5aDENN domain-containing protein 5AS1930.47
DmwdDystrophia myotonica WD repeat-containing proteinT4530.38
Fam76bProtein FAM76BS2270.18
Hip1rHuntingtin-interacting protein 1-related proteinS10450.13
Inpp4bType II inositol 3,4-bisphosphate 4-phosphataseS4700.23
Kansl3KAT8 regulatory NSL complex subunit 3S6310.43
Kdm2aLysine-specific demethylase 2AS4220.29
LrmpLymphoid-restricted membrane proteinS3460.55
Lrrfip1Leucine-rich repeat flightless-interacting protein 1S2840.56
Map4Microtubule-associated protein 4S9730.48
Nfatc3Nuclear factor of activated T-cells, cytoplasmic 3S4160.54
Nup214Nuclear pore complex protein Nup214S10290.37
Pcbp1Poly(rC)-binding protein 1S2460.52
PhaxPhosphorylated adapter RNA export proteinS1550.41
Plekha2Pleckstrin homology domain-containing family A member 2S3490.45
Pola2DNA polymerase alpha subunit BS1260.38
Prrc2aProtein PRRC2AS1660.44
Ptpn22Tyrosine-protein phosphatase non-receptor type 22S4520.52
RdbpNegative elongation factor ES370.21
Reps1RalBP1-associated Eps domain-containing protein 1S4750.50
Rin3Ras and Rab interactor 3S3890.39
Rnf213E3 ubiquitin-protein ligase RNF213S46030.27
Sfr1Swi5-dependent recombination DNA repair protein 1 homologS1390.22
Snx2Sorting nexin-2S2260.38
Supt16hFACT complex subunit SPT16S6500.57
Tbc1d5TBC1 domain family member 5S5460.45
Tsc2Isoform E of TuberinS12540.52
Ube2oUbiquitin-conjugating enzyme E2 OS3940.40
Vps26bVacuolar protein sorting-associated protein 26BS3040.40
Wnk1Serine/threonine-protein kinase WNK1S26250.49
Znf687Zinc finger protein 687S11180.18
Znf687Zinc finger protein 687S4950.43
Znf687Zinc finger protein 687S3510.54