Table I A list of representative regulated proteins involved in focal adhesion pathway
Gene symbolPhosphopeptide sequenceProtein nameSiteTamR/CTRL
PTK2BYIEDEDYyKASVTRLPIKfocal adhesion kinase 2 (FAK2)Y58025.74
RHsMREEDFIQPSSRS7788.91
PTK2YMEDSTYyKASKfocal adhesion kinase 1 (FAK1)Y6622.20
GSIDREDGSLQGPIGNQHIyQPVGKPDPAAPPKY9462.74
SRCY439
FYNWTAPEAALyGRv-src viral oncogeneY4404.21
YESY446
BRAFsPQKPIVRv-raf oncogene homolog BS1510.45
BCAR1RPGPGTLyDVPRbreast cancer anti-estrogen resistance 1Y4337.41
AQQGLyQVPGPSPQFQSPPAKY1748.35
PXNVGEEEHVySFPNKpaxillinY1243.42
FIHQQPQSSsPVyGSSAKY94, S913.64
TLN1STVLQQQyNRtalin 1Y4364.61
TMQFEPSTMVyDACRY265.94
FYNKLDNGGyYITTRFYN oncogeneY2132.80
GAySLSIRY1854.14
CRKYRPAsASVSALIGGRv-crk avian sarcoma virus CT10 oncogeneS1945.89
JUNLAsPELERjun proto-oncogeneS733.68
MAPK8 MAPK10TAGTSFMMTPyVVTRmitogen-activated protein kinase 8, 10Y1850.37
Y226
ACTG1EITALAPsTMKactin, gamma 1S3233.18
ACTBactin, beta
ACTN1HRPELIDyGKactinin, alpha 1Y1934.81
ARHGAP5GGIDNPAITsDQELDDKKRho GTPase activating protein 5S12184.41
RTHsDAsDDEAFTTSKS1173, S11763.91
BADRMsDEFVDSFKKBCL2-associated agonist of cell deathS1184.99
FLNACSGPGLsPGMVRfilamin A, alphaS14595.06
APsVANVGSHCDLSLKS21524.92
ILKNGtLNKHSGIDFKintegrin-linked kinaseT1812.25
PAK2FYDsNTVKp21 protein (Cdc42/Rac)-activated kinase 2S1322.79
DGFPsGTPALNAKS1522.04
PARVASPSVPKsPTPKSPPSRparvin, alphaS5412.72
PPP1CAyGQFSGLNPGGRPITPPRprotein phosphatase 1, catalytic subunit, alpha isozymeY3173.53
PPP1CBYQYGGLNSGRPVtPPRprotein phosphatase 1, catalytic subunit, beta isozymeT3162.49
PPP1R12ALAsTSDIEEKprotein phosphatase 1, regulatory subunit 12AS5075.55
FPTTATKIsPKS4226.37
VASPVQIYHNPtANSFRvasodilator-stimulated phosphoproteinT432.13
VAV2ASsRsPVFTPRvav 2 guanine nucleotide exchange factorS769, S7710.50
VCLILLRNPGNQAAyEHFETMKvinculinY6933.48
DPSAsPGDAGEQAIRS29128.40
ZYXFsPGAPGGSGSQPNQKzyxinS3414.23
sPGAPGPLTLKS4047.30