Table II

Comparison of relative PTM abundances of intact and clipped histone H3 proteoforms. Statistically significant difference is indicated by * (p < 0.05), ** (p < 0.005), and *** (p < 0.0005). No significant difference is indicated by n.s. Marks that are differentially abundant (p < 0.05) between intact and clipped H3 proteoforms are indicated in bold

Relative PTM abundance, %t-test (H3ΔS10 vs Intact H3)t-test (H3ΔG12 vs Intact H3)
Intact H3H3ΔS10H3ΔG12
K14me117.500.1******
K14ac8.617.26.1n.s.n.s.
K18ac1.37.90.5n.s.n.s.
K23ac20.411.816.5n.s.n.s.
K27me14.71.26.7**n.s.
K27me241.858.358.7*****
K27me348.038.033.8*****
K27ac2.71.00n.s.**
K36me11.85.99.9****
K36me22.18.29.1*****
K36me34.40.93.5**n.s.