Table I Patients' characteristics. Table I shows the features of 57 patient samples as measured by SEC-MAP. Acute leukemia (AL) types included B-cell precursor acute lymphoblastic leukemia (BCP-ALL, n = 35), T-cell ALL (T-ALL, n = 9) and acute myeloid leukemia (AML, n = 13). The age at dg. (diagnosis), fusion genes and hyperdiploidy (DNA index > 1,16), and inclusion into Berlin-Frankfurt-Münster risk-groups are indicated (standard risk (SR); median risk (MR), high risk (HR)). “Outcome” is indicated as complete remission (CR) versus relapse (R)
Patient codeType of ALAge at diagnosisMolecular lesionBFM risk-groupOutcome
6B-ALL16ETV6-RUNX1MRR
21B-ALL4ETV6-RUNX1SRCR
30B-ALL4ETV6-RUNX1SRCR
39B-ALL3ETV6-RUNX1SR/MRCR
48B-ALL2ETV6-RUNX1SR/MRCR
54B-ALL3ETV6-RUNX1SRCR
1B-ALL4HyperdiploidyMRCR
2B-ALL8HyperdiploidyMRCR
7B-ALL2HyperdiploidyMRR
14B-ALL2HyperdiploidySRCR
19B-ALL6HyperdiploidySR/MRCR
32B-ALL2HyperdiploidySR/MRCR
34B-ALL4HyperdiploidySRCR
38B-ALL2HyperdiploidySR/MRCR
45B-ALL3HyperdiploidySR/MRCR
47B-ALL8HyperdiploidySR/MRCR
56B-ALL2HyperdiploidyHRCR
37B-ALL4BCR-ABL1Good risk (protocol EsPhALL)R
55B-ALL0.7MLL-AF4MR (protocol Interfant06)CR
4B-ALL14MLLMRCR
20B-ALL2PBX1/E2ASR/MRCR
5B-ALL2NoneSRCR
8B-ALL18NoneN/A (treated off protocol)N/A
9T-ALL9NoneSR/MRCR
10T-ALL14NoneMRCR
12B-ALL13NoneHRCR
13B-ALL3NoneMRCR
15B-ALL9NoneHRCR
17B-ALL2NoneSRCR
26T-ALL2NoneMRR
27T-ALL15NoneHRCR
29B-ALL4NoneSRCR
31B-ALL15NoneHRCR
33T-ALL18NoneHRCR
35B-ALL13NoneHRCR
36B-ALL4NoneSR/MRCR
44T-ALL8NoneSR/MRCR
46B-ALL14NoneMRR
49T-ALL14NoneHRCR
50T-ALL17NoneMRCR
51T-ALL8NoneMRCR
52B-ALL17NoneSRCR
53B-ALL7NoneMRCR
57B-ALL5NoneHRCR
16AML15AML1-ETOSRCR
40AML10CBFb/MYH11SRCR
3AML8MLL/AF9HRCR
22AML0.6MLL-AF9HRR
28AML16MLL-ELLHRR
42AML15MLL-ELLHRR
43AML1.3MLL-ELLHRR
25AML5PML-RARASRCR
11AML15NoneHRR
18AML1.7NoneHRCR
23AML16NoneHRCR
24AML0.5NoneHRCR
41AML15noneHRR