Table II Protein expression differences between D11 blastomeres vs. the 16-cell embryo and between individual D11 blastomeres. The number of sequence-specific peptides used to identify each protein is listed
UniProt IDProtein nameAbbrev.Unique peptidesFunction (UniProt)
Blastomeres vs. Whole 16-cell Embryo
Higher amounts in D11
    A1L3K7Alpha enolaseEno11Glycolysis
    A2BDB0Actin, cytoplasmic 2Actg12Cell motility
    P04751Actin, alpha cardiac muscle 1Actc12Cell structure
    P17508Elongation factor 1-alpha, oocyte formEef1a6Protein synthesis
    P18709Vitellogenin A2Vtga2139Precursor to protein synthesis
    P50143T-complex protein 1 subunit gammaCct34Protein folding, ciliogenesis
    P52301GTP-binding nuclear proteinRan6Nucleocytoplasmic transport, cell cycle control
    Q5FWK8Arachidonate 12-lipoxygenase, 12R-typeAlox12b9Metal (iron) binding
    Q5XHE0TransaldolaseTaldo13Pentose-phosphate pathway
    Q66KY660S ribosomal protein L11Rpl112Protein translation
    Q7ZTK060 kDa heat shock proteinHspd14Protein refolding
    Q7ZTL5Chaperonin containing TCP1, subunit 8 (Theta)Cct82Protein folding
    Q7ZXH6Tyrosine 3-monooxygenaseYwhaq1Monooxygenase activity
    Q8AVI360S acidic ribosomal protein P0Rplp04Protein translation
    Q8AVP6Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1Gnb2l18Gastrulation, cell division, cell polarity
    Q91375Elongation factor 1-gamma-BEef1g-b1Protein synthesis
    Q92122Pyruvate kinasePkm4Regulation of metamorphic processes
Lower amounts in D11
    P15107Superoxide dismutaseSod1-b4Antioxidant
    P17507Elongation factor 1-alpha, oocyte formEef1a-o6Protein synthesis
    P19009Vitellogenin A1Vtga11Storage protein, nutrient
    Q00387Serine protease inhibitor A6Serpina618Endopeptidase inhibitor
    Q6GPT0Fatty acid binding protein 4Fabp47Lipid binding, transport activity
    Q7ZYS160S ribosomal protein L19Rpl193Protein translation
    Q8AVP8Peptidyl-prolyl cis-trans isomerasePpia8Protein folding
    Q9PSX0Fructose-bisphosphate aldolaseAldoc7Glycolysis
Variable Expression between D11 Blastomeres
    A0AUT4Chaperonin containing TCP1, subunit 5Cct53Protein folding
    P17507Elongation factor 1-alpha, oocyte formEef1a-o6Protein synthesis
    P18709Vitellogenin A2Vtga2124Precursor to protein synthesis
    P19009Vitellogenin A1Vtga11Precursor to protein synthesis
    P45695Cofilin 1ACfl1a4Cell morphology, cytoskeletal organization
    P52297Karyopherin (importin) beta 1Kpnb13Nuclear import
    Q3KQ545-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolaseAtic7Convergent extension, axis elongation, Wnt signaling
    Q68EY5ATP synthase subunit alphaAtp5a14ATP production, energy
    Q6DJL4ATPase inhibitory factor 1Atpif14Negative regulation of ATPase activity
    Q6GNF4Ribosomal protein S17Rps175Protein translation
    Q6INS0Glutathione S-transferase theta 1Gstt15Transferase
    Q6NRQ9Glutathione S-transferase omega 2*Gsto24Glutathione transferase activity
    Q6PB22Hyaluronan binding protein 4Habp45Transcription regulation,
    Q7SYU5Fructose-bisphosphate aldolaseAldoa3Glycolysis
    Q7SZF6Vitellogenin B1Vtgb1122Lipid transport, protein synthesis
    Q7ZWR6ATP synthase subunit betaAtp5b20ATP production, energy
    Q7ZY52Glyceraldehyde-3-phosphate dehydrogenaseGapdh8Carbohydrate degradation: Glycolysis
    Q7ZYR1Ribosomal protein L3Rpl34Protein translation
    Q7ZYS8Ribosomal protein L10aRpl10a3Protein translation
    Q801S3Ribosomal protein S3a-ARps3a-a6Protein translation
    Q8AVP6Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1Gnb2l18Gastrulation, cell division, cell polarity
    Q8AVP8Peptidyl-prolyl cis-trans isomerasePpia9Protein folding
    Q9DED4Cold-inducible RNA-binding protein BCirbp-b3Essential for cell movement, neural development, gastrulation
    Q9I9M9Adenine nucleotide translocase*Slc25a56Spinal cord motor neuron differentiation; organ development
    Q9PSX0Fructose-bisphosphate aldolaseAldoc7Glycolysis