Table II Proteins and phosphoproteins involved in cell adhesion/tight junction pathways showing altered expression in Wip1-KO mice
Accession numberProtein descriptionPhosphorylation sitep valueFold changeKOWT
(KO/WT)S.D.S.D.
Q91Z83Myosin-7 (Myosin heavy chain 7)0.0271.6440.3580.061
Q02248Catenin beta-1S (552)0.0210.5800.5320.137
P39447Tight junction protein ZO-1S (617)0.0186.9950.4900.032
P23242Gap junction alpha-1 proteinS (306)0.0060.4180.0970.019
Q62523ZyxinS (336)0.0490.3800.2280.046
Q91YD9Neural Wiskott-Aldrich syndrome proteinY (253)0.0020.4360.0300.038
Q9WTQ5A-kinase anchor protein 12T (635)0.0160.1050.0230.559
Q9WTQ5A-kinase anchor protein 12S (733)0.01823.1341.7970.073
P40124Adenylyl cyclase-associated protein 1S (34)7.58E-060.1090.0240.036
Q61165Sodium/hydrogen exchanger 1S (790)0.0130.2700.7630.116
P14602Heat shock protein beta-1 (HspB1)S (86)0.0390.3870.2520.092
P14602Heat shock protein beta-1 (HspB1)S (15)3.84E-070.5520.3490.870
P17095High mobility group protein HMG-I/HMG-YS (36)0.0330.4140.2110.008
Q8K4L3SupervillinS (857)0.0480.4850.1570.045
Q8K4L3SupervillinS (220)0.0020.5920.0220.165
Q8K4L3SupervillinS (227)0.0020.5920.0220.165
Q61235Beta-2-syntrophinS (373)0.0430.4870.1010.060
O70318Band 4.1-like protein 2S (379)0.0050.4890.0430.044
Q80X82SymplekinS (1256)4.03E-060.5560.1130.172
Q8BRT1CLIP-associating protein 2S (376)0.0183.8900.1960.048
Q99KG5Lipolysis-stimulated lipoprotein receptorS (407)0.0020.3020.1180.108
P59242CingulinS (149)0.0440.4130.2900.084
Q6AW69Cingulin-like protein 1S (284)0.0260.5110.0980.046
Q9JKB3Y-box-binding protein 3S (2)0.0253.4220.1620.916