Table III Statistically increased P(-1) residues between B*51:01 ligands with IR>1.5 from the indicated cell line pairsa
ERAP1 depletion (ERAP2+)ERAP2 depletion (ERAP1+)ERAP1 depletion (ERAP2−)ERAP2 depletion (ERAP1−)ERAP1 + 2 depletion
WTE1KOWTE2KOE2KOE1E2KOE1KOE1E2KOWTE1E2KO
GFRSRSLSL
0.030.021.8E−055.0E−110.032.6E−071.7E−091.1E−053.5E−07
8.6E−110.033.8E−061.7E−091.3E−042.0E−06
PKGLGFGF
0.035.3E−041.3E−036.2E−055.9E−052.6E−062.5E−073.6E−05
2.0E−031.7E−075.6E−074.4E−043.5E−083.5E−05
FAYAY
3.4E−047.6E−085.0E−030.020.02
1.3E−032.4E−100.036.5E−030.02
PPP
4.6E−066.8E−052.2E−06
5.0E−044.4E−042.2E−06
  • aStatistical significance was assessed with the χ2 test with Bonferroni correction. Statistically significant p values (<0.05) are indicated. In the comparisons involving E1E2KO #1 and #19 only those residues showing statistical significance with both clones were considered. The double p values in these comparisons indicate the difference with clones #1 and #19 respectively.