TABLE I

Correlation between alterations detected by CGH and by expression monitoring

Top, CGH used as independent variable (if CGH alteration − what expression ratio was found); bottom, altered expression used as independent variable (if expression alteration − what CGH deviation was found).

CGH alterationsTumor 733 vs. 335ConcordanceCGH alterationsTumor 827 vs. 532Concordance
Expression change clustersExpression change clusters
13 Gain10 Up-regulation77%10 Gain8 Up-regulation80%
0 Down-regulation0 Down-regulation
3 No change2 No change
10 Loss1 Up-regulation50%12 Loss3 Up-regulation17%
5 Down-regulation2 Down regulation
4 No change7 No change
Expression change clustersTumor 733 vs. 335ConcordanceExpression change clustersTumor 827 vs. 532Concordance
CGH alterationsCGH alterations
16 Up-regulation11 Gain69%17 Up-regulation10 Gain59%
2 Loss5 Loss
3 No change2 No change
21 Down-regulation1 Gain38%9 Down-regulation0 Gain33%
8 Loss3 Loss
12 No change6 No change
15 No change3 Gain60%21 No change1 Gain81%
3 Loss3 Loss
9 No change17 No change