Table V Decision ruleset applied in the original TPP analysis workflow [6] to combine z-test p values across replicates in an experimental design with two biological replicates
Rule numberRule
1The Benjamini-Hochberg adjusted z-test p values fulfill predefined thresholds in each replicate.
2Both Tm differences are either positive or negative in the two biological replicates.
3The smallest absolute difference between treatment and vehicle Tm is greater than the absolute Tm difference between the two vehicle experiments.