Table III

Genes isolated by the screen and that had been implicated previously in glycogen accumulation

GeneGlycogen phenotypeDescriptionReference
GAC1LowRegulatory subunit for protein serine/threonine phosphatase Glc733
GLC3Lowα-1,4-glucan branching enzyme29
GLC8LowModulator of protein serine/threonine phosphatase Glc7p29
GSY2LowMajor isoform of glycogen synthase9
IRA2 (GLC4)LowGTPase activating protein for Ras1p and Ras2p29
PIG2LowProtein interacting with Gsy2p; possible regulatory subunit for the protein serine/threonine phosphatase Glc7p35
RIM15LowSerine/threonine protein kinase; positive regulator of IME2 expression and sporulation40
SNF1 (GLC2)LowSerine/threonine protein kinase essential for derepression of glucose-repressed genes29
GDB1HighGlycogen debranching enzyme13
GPH1HighGlycogen phosphorylase11
PFK1HighPhosphofructokinase α subunit32
REG1HighRegulatory subunit for protein phosphatase Glc7p, required for glucose repression38
TPS1 (GLC6)HighTrehalose 6-phosphate synthase29