Table III

Antigen expression in normal urothelium and urothelial papillomas

For simplicity, only staining patterns that differ from those observed in normal urothelium are indicated.

TissueCK 20CK 18CK 5CK 7CK 8CK 13CK 14
Normal urotheliumUmbrella cellsUmbrella cellsAll layersAll layersAll layersIntermediate and basal cellsNegative
Tissue Heterogeneity
Type 1Stronger staining of umbrella cells
Type 2AIntermediate and basal cells
Type 2BIntermediate and basal cellsSome scattered positive cells
Type 2CIntermediate and basal cellsAreas with negative cells
Type 3AIntermediate and basal cellsStronger staining of basal cells
Type 3BIntermediate and basal cellsSome scattered positive cellsStronger staining of basal cells
Type 3CIntermediate and basal cellsSome scattered positive cellsStronger staining of basal cellsSome positive cells
Type 4Intermediate and basal cellsAreas with many negative cells
Type 5AIntermediate cells; no staining of basal cellsNo staining of umbrella cells
Type 5BIntermediate cells; no staining of basal cellsNo staining of umbrella cellsSome basal cells positive