Signaling proteins known to be involved in CSF-1 receptor signaling that bind to a phosphopeptide based on the Tyr-973 autophosphorylation site
| Signaling protein | Interaction with the CSF-1 receptor | References |
|---|---|---|
| c-Cbl | Binds in vivo and in vitro to Tyr-973 and is tyrosine-phosphorylated in response to CSF-1 | 15 , 42–44 , 69 |
| Grb2 | Binds in vivo and in vitro to Tyr-697 | 42 , 46 , 58 , 70–73 |
| SHIP | Tyrosine-phosphorylated in response to CSF-1, can associate with the receptor, a binding site has not been identified | 32 , 46 , 47 , 53 |
| Shp1 | Tyrosine-phosphorylated in response to CSF-1, a binding site on the receptor has not been identified | 49 , 52 |
| Shp2 | Tyrosine-phosphorylated in response to CSF-1, associates with the receptor in some cells, a binding site has not been identified | 53 , 74 , 75 |
| Sos | Associates with the CSF-1 receptor through Grb2 | 42 , 46 , 72 |