Table I

Summary of trafficking and cytoskeletal/motor proteins identified in association with intracellular AQP2 vesicles in inner medullary collecting duct (see supplemental tables for full list)

SNAP, soluble N-ethylmaleimide-sensitive factor attachment protein; SCAMP, secretory carrier membrane protein; ARP, actin-related protein; AP, adaptor protein complex.

Small GTP-binding proteins
    ARF1
    ARF2
    ARF3
    ARF4
    ARF5
    ARF6
    ARFd1
    Rab1
    Rab2
    Rab4B
    Rab5A, -B, -C
    Rab7
    Rab10
    Rab11A, -B
    Rab14
    Rab18
    Rab21
    Rab25
    Rac1
    RalA (immunoblot only)
    RalB
SNAREs and related proteins
    Pantophysin
    Reticulon 4
    α-SNAP
    Synaptotagmin-13
    Syntaxin-5A
    Syntaxin-7
    Syntaxin-12
    Syntaxin-13
    Syntaxin-16
    VAMP2
    VAMP3
    VapA, -B
    Vti1A
Annexins
    Annexin I
    Annexin II
    Annexin IV
    Annexin V
Tetraspan proteins
    Synaptogyrin-2
    SCAMP1
    SCAMP2
    SCAMP3
Coat proteins
    Clathrin heavy chain
    α-COP
    β-COP
    β`-COP
Clathrin adaptors
    AP1 β-1 subunit
    AP2 (several subunits)
Exocyst
    Sec6 (immunoblot only)
    Sec8 (immunoblot only)
Actin cytoskeleton
    β-Actin
    γ-Actin
    ARP 2/3 (several subunits)
    Destrin
    Gelsolin
    β-Spectrin-3
    α-Tropomyosin
Myosins and associated proteins
    Myosin 1C
    Myosin IIA
    Myosin IIB
    Myosin VI
    Myosin IXB
    Myosin light chain 3
    Myosin regulatory light chain-B
    Myosin regulatory light chain-C
Microtubule proteins
    α-Tubulin
    β-Tubulin
Microtubule-based motor proteins
    None
Intermediate filament proteins
    Cytokeratin 8
    Cytokeratin 18
    Cytokeratin 19
Heterotrimeric G-proteins
    Gαi2
    Gαi3
    Gαq
    Gβ1, Gβ2, Gβ3
Miscellaneous
    14-3-3 θ
    14-3-3 ζ
    β-Catenin
    Choroidermia
    Dynamin-II
    gp250
    Mannose 6-phosphate receptor
    Myoferlin
    Sec23A
    Sortilin 1
    Ubiquitin
    Ubiquitin-conjugating enzyme E2N
    Vacuolar proton pump, subunit a
    Vacuolar proton pump, subunit d
    Valosin-containing protein