Table I

Partial list of inorganic phosphate-responsive proteins

n, number of peptides identified; Avg., average change in abundance (phosphate/control).

Protein descriptionnAvg.S.D.Accession no.
Increased abundance
    Extracellular matrix
        α-2-macroglobulin-P451.2538.81Q811S0
AMBP protein (Bikunin)120.00Q07456
        ADAMTS-2110.00Q8C9W3
        Extracellular matrix protein 1105.019.96Q61508
        Polycystin 215.00O35245
        Metallopr. Inhib.1 (TIMP-1)53.150.81P12032
        α-2-HS-glycoprotein71.751.10P29699
    Transcriptional regulators
        Zinc finger protein 30110.00Q60585
        Steroid receptor coactivator-119.09P70366
        Fos-related antigen-1 (FRA-1)23.151.44P48755
    Signaling
        Plectin175.899.21Q9QXS1
        GXII sPLA224.663.51Q9EPR2
        MAPKK 343.352.54O09110
        Citron protein13.13P49025
    Intracellular Regulators
        Butyrate resp. fctr 2 (TIS11D)22.800.33P23949
        Ubi-conjugating enzyme E262.341.64O88738
        Copine I92.143.41Q8C166
    Receptors/transporters
        Na2+-dependent dopamine transport111.11Q61327
        Thrombin receptor (PAR-1)14.55P30558
    Mitochondrial (OXPHOS)
        Cytochrome b5 reductase48.5411.15Q9DCN2
        NADH-ubiquinone oxi. B17.218.33Q7TMF3
        Ubiquinol-cytochrome c reductase24.985.81Q9DB77
        NADH-ubiquinone oxi PDSW44.366.62Q9DCS9
        Adenosine kinase14.35Q91VJ3
        Cytochrome c133.153.46Q9D0M3
        ADP,ATP carrier protein82.802.70P51881
        Hexokinase type II32.582.10O08528
        NAD(P) transhydrogenase92.283.89Q61941
Decreased abundance
    Extracellular matrix
        Decorin (PG-S2)10.33P28654
        Tropomyosin 2 (β-chain)20.330.00P58774
        Periostin50.440.14Q62009
        Osteoglycin (Mimecan)10.45Q62000
        Collagen α1(V)50.480.50O88207
        Emilin 120.540.17Q99K41
        Chondroitin 4-O-sulfotransferase20.560.45Q9JJS3
    Transcriptional regulators
        Nuc. receptor co-repressor 210.07Q9WU42
        α-globin tran. factor CP210.44Q9ERA0
        AT motif-binding factor10.48Q61329
    Signaling
        Serine-protein kinase ATM10.11Q62388
        Transforming protein RhoC30.130.18Q62159
        BMP 3b (GDF-10)10.15P97737
        Tyrosine-protein kinase JAK110.27P52332
    Intracellular Regulators
        JAZ (Zfp346)10.16Q9R0B7
        ECSIT10.38Q9QZH6
        SDF2L120.200.00Q9ESP1
    Receptors/transporters
        Fgfr210.15P21803
        DAAM 210.33Q80U19
    Mitochondrial (β-oxidation)
        Carnitine O-palmitoyltransferase10.31P52825
        Putative D2,D4-dienoyl-CoA10.40Q99MZ7
        Propionyl CoA carboxylase α10.46Q91ZA3
        Acyl-CoA acetyltransferase40.480.30Q8QZT1
        D2,D4-dienoyl-CoA reductase20.560.03Q9WV68
        Acyl-CoA dehydrogenase20.590.02Q9DBL1