Table III

Identification and relative quantification of ER proteins during B cell differentiation

Values given at days 1, 2, 3, and 4 are relative quantities to day 0 (no activation). No Leu means that the protein was identified on a particular day but not quantified. No ID means that the protein was not identified on that particular day. New cluster numbers correspond to clusters in Fig. 6, and old cluster numbers correspond to clusters presented previously (4). SER, sarco(endo)plasmic reticulum; DDOST, dolichyl-diphosphooligosaccharide-protein glycosyltransferase.

Day 0Day 1Day 2Day 3Day 4Old clusterNew cluster
BiP11.541.261.491.96V3
ERp5711.421.271.351.80V3
PDI11.121.211.392.09V3
P511.271.271.552.08V3
ERp7211.471.481.631.98V3
AG-IIβ11.191.331.741.99V3
GRP17010.571.351.571.78V5
Calreticulin11.321.021.171.60V3
Rotamase11.161.141.351.653
GRP9411.401.071.331.68V3
ERp4611.191.100.701.31V12
TRAPδ11.091.261.401.603
Calnexin11.191.010.980.84III8
FKBP211.031.151.141.603
AG-IIα10.97No ID1.49No Leu
ERp2910.840.961.011.26V4
DDOST 48 kDa1No IDNo IDNo Leu1.56
SER ATPase 31No IDNo ID0.90No ID
Ero1α10.671.562.992.352
TRAPα1No IDNo IDNo ID1.020
ERp441No LeuNo LeuNo IDNo IDV
SER ATPase1No IDNo LeuNo LeuNo ID